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Design, Synthesis, and Biological Evaluation of Thieno[3,2-d]pyrimidine Derivatives as Potential Simplified Phosphatidylinositol 3-Kinase alpha (PI3Kα) inhibitors 期刊论文
Chemical biology & drug design, 2018
作者:  Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Song, Kun;  Ruan, Cong
收藏  |  浏览/下载:36/0  |  提交时间:2019/01/08
Mechanistic target of rapamycin inhibition with rapamycin induces autophagy and correlative regulation in white shrimp (Litopenaeus vannamei) 期刊论文
AQUACULTURE NUTRITION, 2018, 卷号: 24, 期号: 5, 页码: 1509-1520
作者:  Liu, Xinwei;  Wang, Mengqiang;  Sun, Guoqiong;  Wang, Baojie;  Jiang, Keyong
收藏  |  浏览/下载:62/0  |  提交时间:2018/12/21
Essential roles of neuropeptide VGF regulated TrkB/mTOR/BICC1 signaling and phosphorylation of AMPA receptor subunit GluAl in the rapid antidepressant-like actions of ketamine in mice 期刊论文
BRAIN RESEARCH BULLETIN, 2018, 卷号: 143, 页码: 58-65
作者:  Shen, Mengxin;  Lv, Dan;  Liu, Xu;  Li, Shuting;  Chen, Yaping
收藏  |  浏览/下载:116/0  |  提交时间:2019/01/08
VGF  Ketamine  TrkB  mTOR  BICC1  
Difuran-substituted quinoxalines as a novel class of PI3K alpha H1047R mutant inhibitors: Synthesis, biological evaluation and structure activity relationship 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 37-49
作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Tang, Qing
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
The mTOR inhibitor AZD8055 overcomes tamoxifen resistance in breast cancer cells by down-regulating HSPB8 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 8, 页码: 1338-1346
作者:  Shi, Jia-jie;  Chen, Si-meng;  Guo, Chen-Liang;  Li, Yi-xue;  Ding, Jian
收藏  |  浏览/下载:22/0  |  提交时间:2019/01/08
Targeting the PI3K/Akt/mTOR signaling pathway by pterostilbene attenuates mantle cell lymphoma progression 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 8, 页码: 782-792
作者:  Yu, Dandan;  Zhang, Yong;  Chen, Gege;  Xie, Yongsheng;  Xu, Zhijian
收藏  |  浏览/下载:53/0  |  提交时间:2019/01/08
Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Gao, Ming-Zhao;  Wang, Hong-Bin;  Chen, Xiang-Ling;  Cao, Wen-Ting;  Fu, Li
收藏  |  浏览/下载:23/0  |  提交时间:2019/01/08
Dopamine Receptor Subtypes Differentially Regulate Autophagy 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 5, 页码: 16
作者:  Wang, Dongmei
收藏  |  浏览/下载:6/0  |  提交时间:2019/11/11
Protopanaxadiol derivative DDPU improves behavior and cognitive deficit in AD mice involving regulation of both ER stress and autophagy 期刊论文
NEUROPHARMACOLOGY, 2018, 卷号: 130, 页码: 77-91
作者:  Guo, Xiaodan;  Lv, Jianlu;  Lu, Jian;  Fan, Lei;  Huang, Xi
收藏  |  浏览/下载:56/0  |  提交时间:2019/01/08
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168 期刊论文
NATURE CELL BIOLOGY, 2018, 卷号: 20, 期号: 3, 页码: 320-+
作者:  Xie, Xiaoduo;  Hu, Hongli;  Tong, Xinyuan;  Li, Long;  Liu, Xiangyuan
收藏  |  浏览/下载:104/0  |  提交时间:2019/01/08


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