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西安交通大学 [1]
江苏大学 [1]
海洋研究所 [1]
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昆明医科大学 [1]
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期刊论文 [8]
发表日期
2018 [8]
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Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
作者:
Wang, Beilei
;
Wu, Jiaxin
;
Wu, Yun
;
Chen, Cheng
;
Zou, Fengming
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/12/25
CDK9
Kinase inhibitor
Structure-activity relationship
Leukemia
A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway
期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 2, 页码: 13
作者:
Guo, Chuan-Long
;
Wang, Li-Jun
;
Zhao, Yue
;
Liu, Hua
;
Li, Xiang-Qian
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/08/21
bromophenol
molecular mechanisms
apoptosis
cell cycle
PI3K
Akt
p38
ERK
ROS
human lung cancer
p21 protects cardiomyocytes against ischemia-reperfusion injury by inhibiting oxidative stress
期刊论文
MOLECULAR MEDICINE REPORTS, 2018, 卷号: 17, 期号: 3
作者:
Li, Hong
;
Zou, Tong
;
Meng, Shuai
;
Peng, Yun-Zhu
;
Yang, Jie-Fu
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/04
ischemia-reperfusion injury
cyclin dependent kinase inhibitor 1A
oxidative stress
cardiomyocyte
NF-E2-related factor-2
tumor protein p53
Antiproliferative effects of the CDK6 inhibitor PD0332991 and its effect on signaling networks in gastric cancer cells
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2018, 卷号: 41, 期号: 5
作者:
Wang, Daguang
;
Sun, Yabin
;
Li, Wei
;
Ye, Fei
;
Zhang, Yang
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/05
PD0332991
gastric cancer
cyclin-dependent kinase 6
ingenuity pathway analysis
A Nestin-Cyclin-Dependent Kinase 5-Dynamin-Related Protein 1 Axis Regulates Neural Stem/Progenitor Cell Stemness via a Metabolic Shift
期刊论文
STEM CELLS, 2018, 卷号: 36, 页码: 589-601
作者:
Wang, Jiancheng
;
Huang, Yinong
;
Cai, Jianye
;
Ke, Qiong
;
Xiao, Jiaqi
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2019/11/26
Nestin
Mitochondria
Dynamin-related protein 1
Metabolism
Neural stem/progenitor cells
Cyclin-dependent kinase 5
Inactivation of Cyclin-Dependent Kinase 5 in Hair Cells Causes Hearing Loss in Mice
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2018, 卷号: 11
作者:
Zhai, Xiaoyan
;
Liu, Chengcheng
;
Zhao, Bin
;
Wang, Yanfei
;
Xu, Zhigang
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  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
inner ear
hair cells
stereocilia
hearing loss
CDK5
Wnt-5a Promotes Neural Development and Differentiation by Regulating CDK5 via Ca2+/Calpain Pathway
期刊论文
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, 卷号: 51, 期号: 6, 页码: 2604-2615
作者:
Shu Yang[1]
;
Xiang Min[2]
;
Zhang Pei[3]
;
Qi Guangjian[4]
;
He Feng[5]
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  |  
浏览/下载:6/0
  |  
提交时间:2019/12/24
Ca2+/calpain signaling
Cyclin-dependent kinase 5
Development
Differentiation
Wnt signaling
Comprehensive integrated analysis of gene expression datasets identifies key anti-cancer targets in different stages of breast cancer.
期刊论文
EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2018, 期号: 16, 页码: 802-810
作者:
MENG-TING GONG
;
WEN-XING LI
;
WEN-WEN LV
;
KAN HE
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2018/09/20
Breast Cancer
Gene Expression
Ribonucleotide Reductase Regulatory Subunit M2
Network
Target Genes
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