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Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916
作者:  Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming
收藏  |  浏览/下载:69/0  |  提交时间:2019/12/25
A series of camptothecin prodrugs exhibit HDAC inhibition activity 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 16, 页码: 4706-4715
作者:  Zhu, Qiwen;  Yu, Xumeng;  Shen, Qianqian;  Zhang, Qiumeng;  Su, Mingbo
收藏  |  浏览/下载:29/0  |  提交时间:2019/01/08
Targeting the PI3K/Akt/mTOR signaling pathway by pterostilbene attenuates mantle cell lymphoma progression 期刊论文
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 8, 页码: 782-792
作者:  Yu, Dandan;  Zhang, Yong;  Chen, Gege;  Xie, Yongsheng;  Xu, Zhijian
收藏  |  浏览/下载:53/0  |  提交时间:2019/01/08
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam. 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 11
作者:  Jin, Qinghao;  Guo, Mingquan;  Li, Xun;  Qiu, Zidong;  Chen, Guilin
收藏  |  浏览/下载:22/0  |  提交时间:2018/12/29
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam. 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:  Li, Xun;  Qiu, Zidong;  Jin, Qinghao;  Chen, Guilin;  Guo, Mingquan
收藏  |  浏览/下载:27/0  |  提交时间:2019/01/08
Anticancer activity of safranal against colon carcinoma is due to induction of apoptosis and G2/M cell cycle arrest mediated by suppression of mTOR/PI3K/Akt pathway 期刊论文
JOURNAL OF BUON, 2018, 卷号: 23, 期号: 3, 页码: 574-578
作者:  Zhang, Yibing;  Zhao, Yong;  Guo, Jianyou;  Cui, Haifeng;  Liu, Sha
收藏  |  浏览/下载:40/0  |  提交时间:2018/08/14
Novel Nitric Oxide Donors of Phenylsulfonylfuroxan and 3-Benzyl Coumarin Derivatives as Potent Antitumor Agents 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 5, 页码: 502-506
作者:  Guo, Yalan;  Wang, Yujie;  Li, Haihong;  Wang, Ke;  Wan, Qi
收藏  |  浏览/下载:31/0  |  提交时间:2019/01/08
Natural small molecule bigelovin suppresses orthotopic colorectal tumor growth and inhibits colorectal cancer metastasis via IL6/STAT3 pathway 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 189-199
作者:  Li, Mingyue;  Yue, Grace Gar-Lee;  Song, Li-Hua;  Huang, Mao-Bo;  Lee, Julia Kin-Ming
收藏  |  浏览/下载:58/0  |  提交时间:2018/07/02
Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity 期刊论文
Nature Immunology, 2018
作者:  Qing Zhang;  Jiacheng Bi;  Xiaodong Zheng;  Yongyan Chen;  Hua Wang
收藏  |  浏览/下载:54/0  |  提交时间:2019/01/31
LncRNA NKILA suppresses colon cancer cell proliferation and migration by inactivating PI3K/Akt pathway 期刊论文
TRANSLATIONAL CANCER RESEARCH, 2018, 卷号: 7, 期号: 6
作者:  Huang, Jian;  Zhao, Lingfeng;  Chen, Wei;  Duan, Jian;  Shrestha, Dibesh
收藏  |  浏览/下载:2/0  |  提交时间:2019/12/04


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