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科研机构
上海药物研究所 [39]
昆明植物研究所 [11]
暨南大学 [7]
深圳先进技术研究院 [4]
成都生物研究所 [4]
山东大学 [4]
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期刊论文 [115]
发表日期
2018 [115]
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Rafoxanide, an organohalogen drug, triggers apoptosis and cell cycle arrest in multiple myeloma by enhancing DNA damage responses and suppressing the p38 MAPK pathway
期刊论文
Cancer letters, 2018, 卷号: 444, 页码: 45-59
作者:
Xiao, Wenqin
;
Xu, Zhijian
;
Chang, Shuaikang
;
Li, Bo
;
Yu, Dandan
收藏
  |  
浏览/下载:103/0
  |  
提交时间:2019/01/08
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:
Zhu, Kongkai
;
Song, Jia-Li
;
Tao, Hong-Rui
;
Cheng, Zhi-Qiang
;
Jiang, Cheng-Shi
收藏
  |  
浏览/下载:102/0
  |  
提交时间:2019/01/08
Pharmacophore combination
Isoquinoline
PRMT5 inhibitor
Molecular docking
Molecular dynamics simulation
Restoration of sternness-high tumor cell-mediated suppression of murine dendritic cell activity and inhibition of tumor growth by low molecular weight oyster polysaccharide
期刊论文
INTERNATIONAL IMMUNOPHARMACOLOGY, 2018, 卷号: 65, 页码: 221-232
作者:
Zhong, Ming
;
Zhong, Cheng
;
Hu, Pei
;
Cui, Wen
;
Wang, Guanghui
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2019/01/08
Colorectal cancer stem cells
Dendritic cells
TGF-beta
NF-kappa B
Oyster polysaccharide
C11, a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses breast cancer metastasis and angiogenesis
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Chen, Zhuo
;
Tong, Lin-Jiang
;
Tang, Bai-You
;
Liu, Hong-Yan
;
Wang, Xin
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  |  
浏览/下载:104/0
  |  
提交时间:2019/01/08
Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma
期刊论文
ONCOGENESIS, 2018, 卷号: 7
作者:
Chen, Wei
;
Zhang, Hao
;
Chen, Zhifeng
;
Jiang, Hao
;
Liao, Liping
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  |  
浏览/下载:109/0
  |  
提交时间:2019/01/08
Bromophenol curcumin analog BCA-5 exerts an antiangiogenic effect through the HIF-1 alpha/VEGF/Akt signaling pathway in human umbilical vein endothelial cells
期刊论文
ANTI-CANCER DRUGS, 2018, 卷号: 29, 期号: 10, 页码: 965-974
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Jiang, Bo
;
Shi, Dayong
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2019/05/15
antiangiogenesis
curcumin analogs
hypoxia-inducible factor-1 alpha
human umbilical vein endothelial cells
vascular endothelial growth factor
Bromophenol curcumin analog BCA-5 exerts an antiangiogenic effect through the HIF-1 alpha/VEGF/Akt signaling pathway in human umbilical vein endothelial cells
期刊论文
ANTI-CANCER DRUGS, 2018, 卷号: 29, 期号: 10, 页码: 965-974
作者:
Guo, Chuanlong
;
Wang, Lijun
;
Jiang, Bo
;
Shi, Dayong
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2018/12/21
antiangiogenesis
curcumin analogs
hypoxia-inducible factor-1 alpha
human umbilical vein endothelial cells
vascular endothelial growth factor
Discovery and biological evaluation of thiobarbituric derivatives as potent p300/CBP inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 20, 页码: 5397-5407
作者:
Lu, Wenchao
;
Xiong, Huan
;
Chen, Yu
;
Wang, Chen
;
Zhang, Hao
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  |  
浏览/下载:142/0
  |  
提交时间:2019/01/08
Drug discovery
Epigenetics
Histone acetyltransferase
P300/CBP
Identification of compound D2923 as a novel anti-tumor agent targeting CSF1R
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 11, 页码: 1768-1776
作者:
Liu, Ying-Qiang
;
Wang, Ya-Nan
;
Lu, Xiao-Yun
;
Tong, Lin-Jiang
;
Li, Yan
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2019/01/08
CSF-1R
small-molecule inhibitor
macrophage
myeloid leukemia
Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway
期刊论文
Journal of Experimental & Clinical Cancer Research, 2018, 卷号: 37, 期号: 1
作者:
Peng,Yulin
;
Wang,Yan
;
Tang,Ning
;
Sun,Dongdong
;
Lan,Yulong
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  |  
浏览/下载:0/0
  |  
提交时间:2024/05/07
Andrographolide
COX-2/NF-κB
Angiogenesis
p300
Breast cancer
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