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CORC

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Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3808-3812
作者:  Zheng, Qiangang;  Chen, Ziqi;  Wan, Huixin;  Tang, Shuai;  Ye, Yan
收藏  |  浏览/下载：234/0  |  提交时间：2019/01/08
Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699
作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi
收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
A Drug with Lipophilicity-Dependent Potency Can Be Metabolically Stable: Discovery of a Potent and Selective Retinoic Acid Receptor-Related Orphan Receptor C2 (RORC2) Inverse Agonist as an Orally Bioavailable Anti-Inflammatory Agent 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 23, 页码: 10412-10414
作者:  Wang, Yibing;  Liu, Hong
收藏  |  浏览/下载：78/0  |  提交时间：2019/01/08
Fragment-based drug discovery of triazole inhibitors to block PDEδ-RAS protein-protein interaction 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 597-609
作者:  Chen, Danqi;  Chen, Yuehong;  Lian, Fulin;  Chen, Liu;  Li, Yanlian
收藏  |  浏览/下载：90/0  |  提交时间：2019/01/08
Ophiorrhines A and B, Two Immunosuppressive Monoterpenoid Indole Alkaloids from Ophiorrhiza japonica 期刊论文
Organic letters, 2018
作者:  Feng, Tao;  Duan, Kai-Ting;  He, Shi-Jun;  Wu, Bin;  Zheng, Yong-Sheng
收藏  |  浏览/下载：79/0  |  提交时间：2019/01/08
Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文
European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689
作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao
收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08
Characteristics of hERG and hNav1.5 channel blockade by sulcardine sulfate, a novel anti-arrhythmic compound 期刊论文
European journal of pharmacology, 2018, 卷号: 844, 页码: 130-138
作者:  Chen, Weihai;  Gan, Lu;  Wang, Yiping
收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08
Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11
iTRAQ-Based Quantitative Proteomic Analysis of a Toxigenic Dinoflagellate Alexandrium catenella at Different Stages of Toxin Biosynthesis during the Cell Cycle 期刊论文
MARINE DRUGS, 2018, 卷号: 16, 期号: 12
作者:  Zhang, Shu-Fei;  Zhang, Yong;  Lin, Lin;  Wang, Da-Zhi
收藏  |  浏览/下载：37/0  |  提交时间：2019/07/15
Phytochemical and chemotaxonomic study on Leathesia nana (Chordariaceae) 期刊论文
BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2018, 卷号: 81, 页码: 42-44
作者:  Xu, Kuo;  Guo, Shuju;  Jia, Xiaoling;  Li, Xiang;  Shi, Dayong
收藏  |  浏览/下载：60/0  |  提交时间：2019/05/15

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