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CORC

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Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81
作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen
收藏  |  浏览/下载：15/0  |  提交时间：2019/01/11
Identification, structure modification, and characterization of potential small-molecule SGK3 inhibitors with novel scaffolds 期刊论文
Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1902-1912
作者:  Gong, Grace Qun;  Wang, Ke;  Dai, Xin-Chuan;  Zhou, Yan;  Basnet, Rajesh
收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08
VAOS, a novel vanadyl complexes of alginate saccharides, inducing apoptosis via activation of AKT-dependent ROS production in NSCLC 期刊论文
FREE RADICAL BIOLOGY AND MEDICINE, 2018, 卷号: 129, 页码: 177-185
作者:  Zhou, Ling;  Yi, Yuetao;  Yuan, Qing;  Zhang, Jing;  Li, Youjie
收藏  |  浏览/下载：20/0  |  提交时间：2020/07/08
Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR 期刊论文
SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873
作者:  Li, R.;  Du, Y.;  Shen, J.
收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08
Lambertellin from Pycnoporus sanguineus MUCL 51321 and its anti-inflammatory effect via modulation of MAPK and NF-kappa B signaling pathways 期刊论文
BIOORGANIC CHEMISTRY, 2018, 卷号: 80, 期号: 2018, 页码: 2016-222
作者:  Jouda, Jean-Bosco;  Njoya, Emmanuel Mfotie;  Mbazoa, Celine Djama;  Zhou, ZongYuan;  Lannang, Alain Meli
收藏  |  浏览/下载：44/0  |  提交时间：2020/12/24
Steroidal alkaloid solanine A from Solanum nigrum Linn. exhibits anti-inflammatory activity in lipopolysaccharide/interferon gamma-activated murine macrophages and animal models of inflammation 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 105, 期号: 2018, 页码: 606-615
作者:  Zhao, Lin;  Wang, Lun;  Di, Suo-ni;  Xu, Qian;  Ren, Qing-cuo
收藏  |  浏览/下载：10/0  |  提交时间：2020/12/24
A natural compound derivative P-13 inhibits STAT3 signaling by covalently inhibiting Janus kinase 2 期刊论文
Investigational new drugs, 2018
作者:  Huang, Hui;  Niu, Junxing;  Wang, Fei;  Hu, Lihong;  Yu, Qiang
收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08
Design, Synthesis, and Biological Evaluation of Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-diones as Potent and Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors against L858R/T790M Resistance Mutation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 61, 期号: 13, 页码: 5609-5622
作者:  Hao, Yongjia;  Lyu, Jiankun;  Qu, Rong;  Tong, Yi;  Sun, Deheng
收藏  |  浏览/下载：65/0  |  提交时间：2019/01/08
Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species 期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 6, 页码: 1048-1063
作者:  Zhong, Chen-chun;  Chen, Feng;  Yang, Jun-ling;  Jia, Wei-wei;  Li, Li
收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08
Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma 期刊论文
Acta pharmacologica Sinica, 2018
作者:  Gao, Ming-Zhao;  Wang, Hong-Bin;  Chen, Xiang-Ling;  Cao, Wen-Ting;  Fu, Li
收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08

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