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科研机构
山东大学 [9]
上海药物研究所 [8]
西安交通大学 [5]
武汉大学 [4]
成都生物研究所 [3]
吉林大学白求恩第三医... [3]
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期刊论文 [56]
学位论文 [1]
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2018 [57]
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发表日期:2018
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Natural flavonoid galangin alleviates microglia-trigged blood-retinal barrier dysfunction during the development of diabetic retinopathy
期刊论文
The Journal of nutritional biochemistry, 2018, 卷号: 65, 页码: 1-14
作者:
Zhang, Tianyu
;
Mei, Xiyu
;
Ouyang, Hao
;
Lu, Bin
;
Yu, Zengyang
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
A new xanthatin analogue 1 beta-hydroxyl-5 alpha-chloro-8-epi-xanthatin induces apoptosis through ROS-mediated ERK/p38 MAPK activation and JAK2/STAT3 inhibition in human hepatocellular carcinoma
期刊论文
BIOCHIMIE, 2018, 卷号: 152, 期号: 2018, 页码: 43-52
作者:
Fang, Xin-Yi
;
Zhang, Hai
;
Zhao, Lin
;
Tan, Shuai
;
Ren, Qing-Cuo
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/12/24
1 beta-hydroxyl-5 alpha-chloro-8-epi-xanthatin
Hepatocellular carcinoma
Apoptosis
Reactive oxygen species
Glutathione
MAPKs and JAK2/STAT3 cascades
Steroidal alkaloid solanine A from Solanum nigrum Linn. exhibits anti-inflammatory activity in lipopolysaccharide/interferon gamma-activated murine macrophages and animal models of inflammation
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2018, 卷号: 105, 期号: 2018, 页码: 606-615
作者:
Zhao, Lin
;
Wang, Lun
;
Di, Suo-ni
;
Xu, Qian
;
Ren, Qing-cuo
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/12/24
Solanine A
Solanum nigrum Linn.
Anti-inflammatory activity
NF-kappa B and MAPKs cascades
PI3K/Akt and JAK/STATs signalings
Targeting Pin1 by inhibitor API-1 regulates microRNA biogenesis and suppresses hepatocellular carcinoma development
期刊论文
HEPATOLOGY, 2018, 卷号: 68, 期号: 2, 页码: 547-560
作者:
Pu, Wenchen
;
Li, Jiao
;
Zheng, Yuanyuan
;
Shen, Xianyan
;
Fan, Xin
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2020/12/24
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy
期刊论文
ACTA PHARMACEUTICA SINICA B, 2018, 卷号: 8, 期号: 4, 页码: 552-562
作者:
Liu, Feifei
;
Yang, Xiaotong
;
Geng, Meiyu
;
Huang, Min
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/01/08
Mitogen-activated protein kinases
Extracellular signal-regulated kinase
ERK inhibitor
ERK kinase
Cancer therapy
Drug resistance
A11, a novel diaryl acylhydrazone derivative, exerts neuroprotection against ischemic injury in vitro and in vivo
期刊论文
Acta pharmacologica Sinica, 2018
作者:
Feng, Hong-Xuan
;
Li, Chun-Pu
;
Shu, Shuang-Jie
;
Liu, Hong
;
Zhang, Hai-Yan
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism
期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 24, 页码: 9370-9387
作者:
Lei, Saifei
;
Clydesdale, Lachlan
;
Dai, Antao
;
Cai, Xiaoqing
;
Feng, Yang
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2019/01/08
G protein-coupled receptor (GPCR)
glucagon
receptor structure-function
cell signaling
site-directed mutagenesis
biased agonism
GLP-1 receptor
glucagon-like peptide-1
class B peptide hormone
ERK kinase
arrestin
transmembrane domain
Cananga odorata essential oil reverses the anxiety induced by 1-(3-chlorophenyl) piperazine through regulating the MAPK pathway and serotonin system in mice
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 219, 页码: 23-30
作者:
Zhang, Nan
;
Zhang, Lei
;
Feng, Linyin
;
Yao, Lei
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
Cananga odorata
1-(3-Chlorophenyl) piperazine
Anxiolytic effect
MAPK
5-HT
Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3
期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:
Xie, Wei
;
Ye, Yangliang
;
Feng, Ying
;
Xu, Tifei
;
Huang, Suling
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/01/08
cAMP
gluconeogenesis
linderane
phosphodiesterase
type 2 diabetes
Immune function against bacteria of chitin deacetylase 1 (EcCDA1) from Exopalaemon carinicauda
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2018, 卷号: 75, 页码: 115-123
作者:
Sun, Yuying
;
Zhang, Jiquan
;
Xiang, Jianhai
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  |  
浏览/下载:40/0
  |  
提交时间:2019/08/21
Exopalaemon carinicauda
Chitin deacetylase
Pichia pastoris
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