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Discovery and structure-activity-relationship study of novel imidazole cyclopropyl amine analogues for mutant isocitric dehydrogenase 1 (IDH1) inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3808-3812
作者:  Zheng, Qiangang;  Chen, Ziqi;  Wan, Huixin;  Tang, Shuai;  Ye, Yan
收藏  |  浏览/下载:236/0  |  提交时间:2019/01/08
3-(7-Azaindolyl)-4-indolylmaleimides as a novel class of mutant isocitrate dehydrogenase-1 inhibitors: Design, synthesis, and biological evaluation 期刊论文
ARCHIV DER PHARMAZIE, 2018, 卷号: 351, 期号: 10
作者:  Hu, Yuanyuan;  Gao, Anhui;  Liao, Honghui;  Zhang, Mengmeng;  Xu, Gaoya
收藏  |  浏览/下载:33/0  |  提交时间:2019/01/08
Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells 期刊论文
HAEMATOLOGICA, 2018, 卷号: 103, 期号: 9, 页码: 1472-1483
作者:  Wu, Dang;  Wang, Wanyan;  Chen, Wuyan;  Lian, Fulin;  Lang, Li
收藏  |  浏览/下载:37/0  |  提交时间:2019/01/08
Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846
作者:  Liang, Xiaofei;  Li, Feng;  Chen, Cheng;  Jiang, Zongru;  Wang, Aoli
收藏  |  浏览/下载:15/0  |  提交时间:2019/12/10
Current Strategies and Applications for Precision Drug Design 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9
作者:  Wang, Chen;  Xu, Pan;  Zhang, Luyu;  Huang, Jing;  Zhu, Kongkai
收藏  |  浏览/下载:48/0  |  提交时间:2019/01/08
Identification of Potential Key Genes Associated With the Pathogenesis and Prognosis of Gastric Cancer Based on Integrated Bioinformatics Analysis 期刊论文
FRONTIERS IN GENETICS, 2018, 卷号: 9, 页码: 265
作者:  Zhang, Dan;  Bing, Zhitong;  Tian, Jinhui;  Ni, Mengwei;  Wu, Jiarui
收藏  |  浏览/下载:38/0  |  提交时间:2018/10/08
Saponins From Paris forrestii (Takht.) H. Li Display Potent Activity Against Acute Myeloid Leukemia by Suppressing the RNF6/AKT/mTOR Signaling Pathway 期刊论文
FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9, 页码: 673
作者:  Lu, Qin;  He, Yuanming;  Wang, Yuehu;  Gao, Li;  Zheng, Yunjing
收藏  |  浏览/下载:35/0  |  提交时间:2018/07/30
Novel Therapy for FLT3-ITD Acute Myeloid Leukemia Utilizing the Combination of CUDC-907 and Gilteritinib 期刊论文
BLOOD, 2018, 卷号: 132
作者:  Knight, Tristan;  Qiao, Xinan;  Edwards, Holly;  Lin, Hai;  Taub, Jeffrey W.
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/05
Circular RNA-100290 promotes cell proliferation and inhibits apoptosis in acute myeloid leukemia cells via sponging miR-203 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 卷号: 507, 期号: 1-4
作者:  Fan, Hongqiong;  Li, Yuying;  Liu, Chunshui;  Liu, Yingmin;  Bai, Jing
收藏  |  浏览/下载:4/0  |  提交时间:2019/12/05
Chidamide, Decitabine, Cytarabine, Aclarubicin, and Granulocyte Colony Stimulating Factor (CDCAG) in Adults with Relapsed/Refractory Acute Myeloid Leukemia: Final Results from a Phase 1/2 Study 期刊论文
BLOOD, 2018, 卷号: 132
作者:  Wang, Lixin;  Chen, Guofeng;  Shen, Jianliang;  Luo, Jianmin;  Fang, Meiyun
收藏  |  浏览/下载:12/0  |  提交时间:2019/12/05


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