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上海生物化学与细胞生... [9]
内容类型
期刊论文 [9]
发表日期
2018 [9]
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发表日期:2018
专题:上海生物化学与细胞生物学研究所
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Efficient CRISPR-based genome editing using tandem guide RNAs and editable surrogate reporters
期刊论文
FEBS OPEN BIO, 2018, 卷号: 8, 期号: 7, 页码: 1167-1175
作者:
Liu, Wuqing
;
Li, Shifeng
;
Zhang, Yunbin
;
Li, Jinsong
;
Li, Yiping
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/04/28
Off-target
Cas9 Nucleases
Sgrna Design
In-vivo
Cells
Dna
Systems
Gene
Identification
Specificity
GOLPH2-regulated oncolytic adenovirus, GD55, exerts strong killing effect on human prostate cancer stem-like cells in vitro and in vivo
期刊论文
ACTA PHARMACOLOGICA SINICA, 2018, 卷号: 39, 期号: 3, 页码: 405-414
作者:
Ying, Chang
;
Xiao, Bo-duan
;
Qin, Yun
;
Wang, Bin-rong
;
Liu, Xin-yuan
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/04/28
Potent Antitumor-activity
Colorectal-cancer
Gene
Identification
Heterogeneity
Plasticity
Resistance
Xenograft
Promoter
Efficacy
CRISPR-Cas9-mediated base-editing screening in mice identifies DND1 amino acids that are critical for primordial germ cell development
期刊论文
NATURE CELL BIOLOGY, 2018, 卷号: 20, 期号: 11, 页码: 1315-+
作者:
Li, Qing
;
Yang, Suming
;
Yan, Meng
;
Ding, Yifu
;
Yin, Qi
收藏
  |  
浏览/下载:112/0
  |  
提交时间:2019/04/28
Embryonic Stem-cells
Mouse Embryos
Ter Mutation
Dna Cleavage
Genomic Dna
Gene
Generation
Sites
Complex
Rnas
Single cell clustering based on cell-pair differentiability correlation and variance analysis
期刊论文
BIOINFORMATICS, 2018, 卷号: 34, 期号: 21, 页码: 3684-3694
作者:
Jiang, Hao
;
Sohn, Lydia L.
;
Huan, Haiyan
;
Chen, Luonan
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/04/28
Embryonic Stem-cells
Rna-seq
Microenvironment
Challenges
Genes
H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells
期刊论文
PLOS BIOLOGY, 2018, 卷号: 16, 期号: 11, 页码: -
作者:
Wang, Lijun
;
Niu, Ningning
;
Li, Li
;
Sheo, Rui
;
Ouyang, Huiling
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/04/28
Lipopolysaccharide-binding Protein
Induced Liver-injury
Lysine 36
Histone
Differentiation
Adipogenesis
Methylation
Adipocyte
Identification
Hypb/setd2
Apj(+) Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target
期刊论文
CELL REPORTS, 2018, 卷号: 25, 期号: 5, 页码: 1241-+
作者:
Zhao, Huan
;
He, Lingjuan
;
Li, Yan
;
Pu, Wenjuan
;
Liu, Qiaozhen
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/04/28
Protein-coupled Receptor
In-vivo
Apelin-apj
Endothelial-cells
Angiogenic Factor
Genetic Ablation
Transgenic Mice
Toxin Gene
T-cells
Expression
Phf8 histone demethylase deficiency causes cognitive impairments through the mTOR pathway
期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9, 期号: 1, 页码: 114
作者:
Chen, Xuemei
;
Wang, Shuai
;
Zhou, Ying
;
Han, Yanfei
;
Li, Shengtian
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  |  
浏览/下载:44/0
  |  
提交时间:2019/04/28
Linked Mental-retardation
Cleft lip/Cleft Palate
Synaptic Plasticity
Protein-synthesis
Cell-cycle
Gene
Mutations
Memory
Identification
Differentiation
Identification of recurrent USP48 and BRAF mutations in Cushing's disease
期刊论文
NATURE COMMUNICATIONS, 2018, 卷号: 9, 期号: 1, 页码: 3171
作者:
Chen, Jianhua
;
Jian, Xuemin
;
Song, Zhijian
;
Li, Zhiqiang
;
Zhou, Juan
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2019/04/28
Human Cancer
Proopiomelanocortin Gene
Deubiquitinating Enzyme
Pituitary-adenomas
Kappa-b
Transcription
Activation
Raf
Pathways
Genome
In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 17, 页码: E3978-E3986
作者:
Wu, Qibiao
;
Zhang, Jian
;
Tong, Xinyuan
;
Huang, Hsinyi
;
Tang, Ying
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/04/28
Lysine-4 Methyltransferase Complex
Acute Lymphoblastic-leukemia
K-ras
Cancer
Adenocarcinoma
Polycomb
Cells
Differentiation
Expression
Identification
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