QQ客服 官方微博 反馈留言

浏览/检索结果: 共145条，第1-10条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Baicalin relaxes vascular smooth muscle and lowers blood pressure in spontaneously hypertensive rats 期刊论文 Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, 卷号: 111, 页码: 325-330 作者:  Ding, Liliqiang;  Jia, Chenglin;  Zhang, Yong;  Wang, Wenjian;  Zhu, Weiliang 收藏  |  浏览/下载：98/0  |  提交时间：2019/01/08 Discovery of new potent protein arginine methyltransferase 5 (PRMT5) inhibitors by assembly of key pharmacophores from known inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 28, 期号: 23-24, 页码: 3693-3699 作者:  Zhu, Kongkai;  Song, Jia-Li;  Tao, Hong-Rui;  Cheng, Zhi-Qiang;  Jiang, Cheng-Shi 收藏  |  浏览/下载：101/0  |  提交时间：2019/01/08 Pharmacophore combination  Isoquinoline  PRMT5 inhibitor  Molecular docking  Molecular dynamics simulation   Ophiorrhines A and B, Two Immunosuppressive Monoterpenoid Indole Alkaloids from Ophiorrhiza japonica 期刊论文 Organic letters, 2018 作者:  Feng, Tao;  Duan, Kai-Ting;  He, Shi-Jun;  Wu, Bin;  Zheng, Yong-Sheng 收藏  |  浏览/下载：81/0  |  提交时间：2019/01/08 Discovery and optimization of a series of 3-substituted indazole derivatives as multi-target kinase inhibitors for the treatment of lung squamous cell carcinoma 期刊论文 European journal of medicinal chemistry, 2018, 卷号: 163, 页码: 671-689 作者:  Wang, Qi;  Dai, Yang;  Ji, Yinchun;  Shi, Huanyu;  Guo, Zuhao 收藏  |  浏览/下载：86/0  |  提交时间：2019/01/08 Characteristics of hERG and hNav1.5 channel blockade by sulcardine sulfate, a novel anti-arrhythmic compound 期刊论文 European journal of pharmacology, 2018, 卷号: 844, 页码: 130-138 作者:  Chen, Weihai;  Gan, Lu;  Wang, Yiping 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 Design and optimization of 2,3-dihydrobenzo[b][1,4]dioxine propanoic acids as novel GPR40 agonists with improved pharmacokinetic and safety profiles 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 22, 页码: 5780-5791 作者:  Guo, Bin;  Guo, Shimeng;  Huang, Jing;  Li, Jingya;  Li, Jia 收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 GPR40 agonist  2,3-Dihydrobenzo[b][1,4]dioxine  Insulin secretion  Type 2 diabetes mellitus   Development of an LC-MS/MS-based assay to determine artemitin in rat plasma and its application in a pharmacokinetic study 期刊论文 Biomedical chromatography : BMC, 2018, 卷号: 32, 期号: 12, 页码: e4356 作者:  Han, Xiaoli;  He, Jinhua;  Chen, Qinyue;  Sun, Yali;  Zhang, Xiulei 收藏  |  浏览/下载：47/0  |  提交时间：2019/01/08 A pectin from fruits of Lycium barbarum L. decreases Beta-amyloid peptide production through modulating APP processing 期刊论文 CARBOHYDRATE POLYMERS, 2018, 卷号: 201, 页码: 65-74 作者:  Zhou, Lishuang;  Liao, Wenfeng;  Zeng, Hui;  Yao, Yanli;  Chen, Xia 收藏  |  浏览/下载：153/0  |  提交时间：2019/01/08 Lycium barbarum L.  Pectin  A beta(42)  Alzheimer's disease  Amyloid precursor protein processing   Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection 期刊论文 JOURNAL OF PHARMACOLOGICAL SCIENCES, 2018, 卷号: 138, 期号: 4, 页码: 247-256 作者:  Yao, Xingang;  Guo, Songxin;  Wu, Wenyu;  Wang, Jinan;  Wu, Shengen 收藏  |  浏览/下载：104/0  |  提交时间：2019/01/08 RdRp inhibitor  Quinazolinone derivative  DENV2 infection   ETA as a novel Kv2.1 inhibitor ameliorates beta-cell dysfunction and hyperglycaemia 期刊论文 CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2018, 卷号: 45, 期号: 12, 页码: 1257-1264 作者:  Zhou, Tingting;  Du, Mengfan;  Zhao, Tong;  Quan, Lingling;  Zhu, Zhiyuan 收藏  |  浏览/下载：94/0  |  提交时间：2019/01/08 beta cell  apoptosis  glucose-stimulated insulin secretion  T2DM