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浏览/检索结果: 共8条，第1-8条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Pyrazolo[4,3-b]pyrimido[4,5-e][1,4]diazepine derivatives as new multi-targeted inhibitors of Aurora A/B and KDR 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 428-441 作者:  Zhang, Qiumeng;  Shen, Qianqian;  Gao, Lixin;  Tong, Linjiang;  Li, Jia 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Aurora A  Aurora B  KDR  Multi-targeted  Anticancer  Heterocyclic   Synthesis, biological evaluation and structure-activity relationship of a novel class of PI3K alpha H1047R mutant inhibitors 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 707-719 作者:  Zhang, Ning;  Yu, Zhimei;  Yang, Xiaohong;  Zhou, Yan;  Wang, Jia 收藏  |  浏览/下载：89/0  |  提交时间：2019/01/08 Anticancer drug  Phosphatidylinositol 3-kinase  Structure-activity relationship   Synthesis and In Vitro Antitumor Activity of Novel Bivalent -Carboline-3-carboxylic Acid Derivatives with DNA as a Potential Target 期刊论文 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 卷号: 19, 期号: 10 作者:  Gu, Hongling;  Li, Na;  Dai, Jiangkun;  Xi, Yaxi;  Wang, Shijun 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 bivalent -carbolines  antitumor  apoptosis  DNA-binding affinity  bcl-2   Emodin induces apoptosis in human hepatocellular carcinoma HepaRG cells via the mitochondrial caspase‑dependent pathway 期刊论文 Oncology reports, 2018, 卷号: 40, 期号: 4, 页码: 1985-1993 作者:  Dong, Xiaoxv;  Ni, Boran;  Fu, Jing;  Yin, Xingbin;  You, Longtai 收藏  |  浏览/下载：21/0  |  提交时间：2019/01/08 New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis 期刊论文 BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264 作者:  Tian, Qian-Ting;  Ding, Chun-Yong;  Song, Shan-Shan;  Wang, Ying-Qing;  Zhang, Ao 收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 Tanshinone-1  S222  S439  Anticancer targets  DNA topoisomerases  P53   DCZ3301, a novel aryl-guanidino inhibitor, induces cell apoptosis and cell cycle arrest via suppressing the PI3K/AKT pathway in T-cell leukemia/lymphoma 期刊论文 ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2018, 卷号: 50, 期号: 7, 页码: 643-650 作者:  Xiao, Wenqin;  Li, Bo;  Sun, Xi;  Yu, Dandan;  Xie, Yongsheng 收藏  |  浏览/下载：85/0  |  提交时间：2019/01/08 DCZ3301  T-cell leukemia/lymphoma  apoptosis  cell cycle  PI3K/AKT   Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam. 期刊论文 FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9 作者:  Li, Xun;  Qiu, Zidong;  Jin, Qinghao;  Chen, Guilin;  Guo, Mingquan 收藏  |  浏览/下载：27/0  |  提交时间：2019/01/08 colon cancer  Toddalia asiatica Lam.  G2/M arrest  apoptosis  reactive oxygen species   dcz3301anovelarylguanidinoinhibitorinducescellapoptosisandcellcyclearrestviasuppressingthepi3kaktpathwayintcellleukemialymphoma 期刊论文 actabiochimicaetbiophysicasinica, 2018, 卷号: 50, 期号: 7, 页码: 643 作者:  Xiao Wenqin;  Li Bo;  Sun Xi;  Yu Dandan;  Xie Yongsheng 收藏  |  浏览/下载：43/0  |  提交时间：2020/07/01 ACUTE LYMPHOBLASTIC-LEUKEMIA  NON-HODGKIN-LYMPHOMA  SIGNALING PATHWAYS  DEATH  PROTEIN  LINES  DCZ3301  T-cell leukemia/lymphoma  apoptosis  cell cycle  PI3K/AKT