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浏览/检索结果: 共22条，第1-10条 帮助 限定条件 发表日期：2018    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Identification of a cellularly active SIRT6 allosteric activator 期刊论文 NATURE CHEMICAL BIOLOGY, 2018, 卷号: 14, 期号: 12, 页码: 1118-+ 作者:  Huang, Zhimin;  Zhao, Junxing;  Deng, Wei;  Chen, Yingyi;  Shang, Jialin 收藏  |  浏览/下载：91/0  |  提交时间：2019/01/08 A Novel Rhein Derivative Modulates Bone Formation and Resorption and Ameliorates Estrogen-Dependent Bone Loss 期刊论文 Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2018 作者:  Jiang, Min;  Wang, Tianqi;  Yan, Xueming;  Liu, Zhuochao;  Yan, Yufei 收藏  |  浏览/下载：100/0  |  提交时间：2019/01/08 Artificial intelligence in drug design 期刊论文 SCIENCE CHINA-LIFE SCIENCES, 2018, 卷号: 61, 期号: 10, 页码: 1191-1204 作者:  Zhong, Feisheng;  Xing, Jing;  Li, Xutong;  Liu, Xiaohong;  Fu, Zunyun 收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 drug design  artificial intelligence  deep learning  QSAR  ADME/T   Pharmacological Characterization of Dezocine, a Potent Analgesic Acting as a kappa Partial Agonist and mu Partial Agonist 期刊论文 SCIENTIFIC REPORTS, 2018, 卷号: 8 作者:  Wang, Yu-Hua;  Chai, Jing-Rui;  Xu, Xue-Jun;  Ye, Ru-Feng;  Zan, Gui-Ying 收藏  |  浏览/下载：92/0  |  提交时间：2019/01/08 Enhancement of Glucose Utilization by Loesenerine through AMPK Activation in Myotubes 期刊论文 CHEMICAL & PHARMACEUTICAL BULLETIN, 2018, 卷号: 66, 期号: 9, 页码: 885-886 作者:  Wang, Luo-Na;  Jiang, Hao-Wen;  Li, Jin-Long;  Li, Jing-Ya 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 loesenerine  spermidine alkaloid  AMP-activated protein kinase activation  glucose uptake   7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 14, 页码: 4254-4263 作者:  Sun, Hui-jiao;  Wang, Yu-hua;  Yuan, Cong-min;  Kong, Ling-hui;  Xu, Xue-jun 收藏  |  浏览/下载：82/0  |  提交时间：2019/01/08 7 beta-Methyl-nepenthone analogues  KOR ligands  Concept of hybridization  Opioid receptor binding and functional activities   Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity 期刊论文 EBioMedicine, 2018, 卷号: 34, 页码: 201-213 作者:  Fan, Hui-Ran;  Du, Wei-Feng;  Zhu, Tao;  Wu, Yan-Jiao;  Liu, Yan-Mei 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 SIRT1 activator E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression 期刊论文 Atherosclerosis, 2018, 卷号: 274, 页码: 172-181 作者:  Feng, Tingting;  Liu, Peng;  Wang, Xiao;  Luo, Jinque;  Zuo, Xuan 收藏  |  浏览/下载：40/0  |  提交时间：2019/01/08 Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 76-86 作者:  Geng, Kaijun;  Liu, Hongchun;  Song, Zilan;  Zhang, Chi;  Zhang, Minmin 收藏  |  浏览/下载：178/0  |  提交时间：2019/01/08 Heat shock protein 90 (Hsp90)  Tyrosine kinase ALK  Dual inhibitor  Drug resistance  Antiproliferative activity   Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3 期刊论文 FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9 作者:  Xie, Wei;  Ye, Yangliang;  Feng, Ying;  Xu, Tifei;  Huang, Suling 收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 cAMP  gluconeogenesis  linderane  phosphodiesterase  type 2 diabetes