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上海药物研究所 [7]
北京大学 [2]
大连理工大学 [1]
化学研究所 [1]
成都生物研究所 [1]
大连化学物理研究所 [1]
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期刊论文 [14]
发表日期
2017 [14]
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Biochemist... [1]
Chemistry [1]
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Discovery of potent 2,4-difluoro-linker poly(ADP-ribose) polymerase 1 inhibitors with enhanced water solubility and in vivo anticancer efficacy
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1521-1532
作者:
Chen, Wen-hua
;
Song, Shan-shan
;
Qi, Ming-hui
;
Huan, Xia-juan
;
Wang, Ying-qing
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
PARP-1 inhibitor
olaparib
breast cancer
BRCA-deficient tumors
A novel bone marrow targeted gadofullerene agent protect against oxidative injury in chemotherapy
期刊论文
SCIENCE CHINA-MATERIALS, 2017, 卷号: 60, 期号: 9, 页码: 866-880
作者:
Zhang, Ying
;
Shu, Chunying
;
Zhen, Mingming
;
Li, Jie
;
Yu, Tong
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/04/09
Gadofullerene Nanocrystals
Chemopreventive Agent
Myelosuppression
Radical Scavenging
Chemotherapy Drug
Simultaneous determination of eight B-vitamins in rat intestinal perfusate to identify effects of osmotic pressures on absorptions
期刊论文
BIOMEDICAL CHROMATOGRAPHY, 2017, 卷号: 31, 期号: 9
作者:
Wang, Xiaobo
;
Xiao, Jian
;
Zhou, Hui
;
Qiu, Ying
;
Peng, Hui
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
B-vitamins
HPLC-DAD
intestinal perfusate
osmotic pressures
Structural Characterization of Mannoglucan from Dendrobium nobile Lindl and the Neuritogenesis-Induced Effect of Its Acetylated Derivative on PC-12 Cells
期刊论文
POLYMERS, 2017, 卷号: 9, 期号: 9
作者:
Jin, Can
;
Du, Zhenyun
;
Lin, Liyan
;
Zhou, Lishuang
;
Li, Saijuan
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
mannoglucan
polysaccharide
Dendrobium nobile Lindl
neuritogenesis
neurodegeneration disease
Detecting Proteins Glycosylation by a Homogeneous Reaction System with Zwitterionic Gold Nanoclusters
期刊论文
ANALYTICAL CHEMISTRY, 2017, 卷号: 89, 期号: 8, 页码: 4339-4343
作者:
Liu, Xiaoyan
;
Li, Jinan
;
Liu, Jing
;
Liu, Zheyi
;
Tan, Yuan
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  |  
浏览/下载:10/0
  |  
提交时间:2017/10/29
Characterization, Molecular Docking, and In Vitro Dissolution Studies of Solid Dispersions of 20(S)-Protopanaxadiol
期刊论文
MOLECULES, 2017, 卷号: 22, 期号: 2
作者:
Zhang, Qi
;
Pu, Yiqiong
;
Wang, Bing
;
Wang, Yuqin
;
Dong, Tina Tingxia
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
20(S)-protopanaxadiol
solid dispersion
polymer
molecular docking
in vitro dissolution
Amino acids as co-amorphous excipients for tackling the poor aqueous solubility of valsartan
期刊论文
PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 2017, 卷号: 22, 期号: 1, 页码: 69-76
作者:
Huang, Ying
;
Zhang, Qi
;
Wang, Jian-Rong
;
Lin, Kai-Lei
;
Mei, Xuefeng
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Amino acid
co-amorphous
intrinsic dissolution rate
small molecular excipients
solubility
valsartan
Preparation, characterization and in vivo pharmacokinetic study of PVP-modified oleanolic acid liposomes
期刊论文
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2017, 卷号: 517, 期号: 1-2, 页码: 1-7
作者:
Liu, Yan
;
Luo, Xiao
;
Xu, Xiaochao
;
Gao, Nannan
;
Liu, Xiaohong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Oleanolic acid
Liposomes
Polyvinylpyrrolidone
Sodium deoxycholate
Bioavailability
Formulation and Characterization of a Ternary Inclusion Complex Containing Hydroxypropyl-beta-cyclodextrin and Meglumine for Solubility Enhancement of Poorly Water-Soluble ST-246, an Anti-Smallpox Drug
期刊论文
CURRENT DRUG DELIVERY, 2017, 卷号: 14, 页码: 1130-1143
作者:
Li, Xiaoxi
;
Yang, Meiyan
;
Li, Yueqing
;
Gong, Wei
;
Wang, Yuli
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/03
Poorly water-soluble drug
solubilization
inclusion complex
2-hydroxypropyl-beta-cyclodextrin
meglumine
scanning electron microscope (SEM)
Synthesis and pH-dependent hydrolysis profiles of mono- and dialkyl substituted maleamic acids
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2017
Su, Shan
;
Du, Fu-Sheng
;
Li, Zi-Chen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
DRUG-DELIVERY
GENE DELIVERY
SUPRAMOLECULAR ASSEMBLIES
RESPONSIVE NANOPARTICLES
BIOMEDICAL APPLICATIONS
POLYMERIC MICELLES
AMIDE HYDROLYSIS
PHTHALAMIC ACID
RELEASE
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