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科研机构
上海药物研究所 [5]
复旦大学上海医学院 [2]
合肥物质科学研究院 [2]
南海海洋研究所 [1]
新疆理化技术研究所 [1]
湖南农业大学 [1]
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期刊论文 [13]
发表日期
2017 [13]
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Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 卷号: 19, 期号: 44, 页码: 30239-30248
作者:
Chen, Jianzhong
;
Wang, Jinan
;
Zhu, Weiliang
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway
期刊论文
CELL DEATH & DISEASE, 2017, 卷号: 8
作者:
Sun, Xi
;
Li, Bo
;
Xie, Bingqian
;
Xu, Zhijian
;
Chang, Gaomei
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  |  
浏览/下载:64/0
  |  
提交时间:2019/01/08
Structure-activity relationship investigation for benzonaphthyridinone derivatives as novel potent Bruton's tyrosine kinase (BTK) irreversible inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 137, 页码: 545-557
作者:
Wang, Beilei
;
Deng, Yuanxin
;
Chen, Yongfei
;
Yu, Kailin
;
Wang, Aoli
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  |  
浏览/下载:43/0
  |  
提交时间:2018/08/16
Btk
Kinase Inhibitor
Irreversible Inhibitor
Structure-activity Relationship
B-cell Lymphoma
Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl) phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 131, 页码: 107-125
作者:
Liang, Qianmao
;
Chen, Yongfei
;
Yu, Kailin
;
Chen, Cheng
;
Zhang, Shouxiang
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  |  
浏览/下载:39/0
  |  
提交时间:2018/07/26
Btk
Irreversible Inhibitor
Kinase Inhibitor
Structure-activity Relationship
B-cell Lymphoma
Marine-derived chromopeptide A, a novel class I HDAC inhibitor, suppresses human prostate cancer cell proliferation and migration
期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 4, 页码: 551-560
作者:
Sun, Jing-ya
;
Wang, Ji-dong
;
Wang, Xin
;
Liu, Hong-chun
;
Zhang, Min-min
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  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
HDAC
chromopeptide A
FK228
human prostate cancer
cell cycle arrest
apoptosis
cancer cell migration
PC3 xenograft model
Luteolin induces apoptosis in vitro through suppressing the MAPK and PI3K signaling pathways in gastric cancer
期刊论文
ONCOLOGY LETTERS, 2017, 卷号: 14, 期号: 2, 页码: 1993-2000
作者:
Lu, XY (Lu, Xueying)
;
Li, YH (Li, Yanhong)
;
Li, XB (Li, Xiaobo)
;
Aisa, HA (Aisa, Haji Akber)
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  |  
浏览/下载:19/0
  |  
提交时间:2017/12/11
Luteolin
Gastric Carcinoma
Mapk
Pi3k
Dusps
Cxcl16
Altered expression of microRNA-98 in IL-1 beta-induced cartilage degradation and its role in chondrocyte apoptosis
期刊论文
MOLECULAR MEDICINE REPORTS, 2017, 卷号: 16, 期号: 3
作者:
Ma, Sha
;
Wang, Jing
;
Chen, Lingqing
;
Jin, Song
;
Lin, Jun
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/04
microRNA-98
osteoarthritis chondrocytes
B-cell lymphoma-2
apoptosis-associated proteins
interleukin-1 beta
Early anthracycline-induced cardiotoxicity monitored by echocardiographic Doppler parameters combined with serum hs-cTnT
期刊论文
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES, 2017, 卷号: 34, 期号: 11
作者:
Zhang, Chu-Jie
;
Pei, Xiao-Li
;
Song, Fei-Yan
;
Guo, Ye
;
Zhang, Qun-Ling
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/05
anthracycline
cardiotoxicity
diffuse large B-cell lymphoma
echocardiography
high-sensitivity cardiac troponin T
Altered expression of microRNA-98 in IL-1β-induced cartilage degradation and its role in chondrocyte apoptosis
期刊论文
Molecular Medicine Reports, 2017, 卷号: 16, 期号: 3
作者:
Wang, Jing[0]
;
Chen, Lingqing[1]
;
Jin, Song[2]
;
Lin, Jun[3]
;
Zheng, Hongmei[4]
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Apoptosis-associated proteins
B-cell lymphoma-2
Interleukin-1β
microRNA-98
Osteoarthritis chondrocytes
Toxicity study of oxalicumone A, derived from a marine-derived fungus Penicillium oxalicum, in cultured renal epithelial cells
期刊论文
MOLECULAR MEDICINE REPORTS, 2017, 卷号: 15, 期号: 5, 页码: 2611-2619
作者:
Shi, S
;
Guo, KB
;
Wang, XG
;
Chen, H
;
Min, JB
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  |  
浏览/下载:26/0
  |  
提交时间:2017/09/08
Penicillium oxalicum
oxalicumone A
human kidney-2 cells
cytotoxicity
apoptosis
mitochondria
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