AIs  aromatase inhibitors  AMPK  Adenosine Monophosphate-Activated Protein Kinase  AR  androgen  ATM  Ataxia Telangiectasia Mutated  ATP  Adenosine Triphosphate  BCSS  breast cancer specific survival  CK-MB  Creatine Kinase-MB  CREB1  cAMP Response Element-Binding Protein 1  CSC  cancer stem cell  DFS  disease-free survival  DHFU  dihydrofluorouracil  DPD  dihydropyrimidine dehydrogenase  EpCAM  Epithelial Cell Adhesion Molecule  ER  estrogen  ERCC1  excision repair cross-complementary 1  ERK  extracellular signal-regulated kinases  EZH2  enhancer of zeste homolog 2  FdUMP  fluorodeoxyuridine monophosphate  FdUTP  fluorodeoxyuridine triphosphate  FHC  ferritin heavy chain  FUTP  fluorouridine triphosphate  HbA1C  hemoglobin A1c  HER  Human Epidermal Growth Factor Receptor  HIF-1α  hypoxia-inducible factor-1α  HK  hexokinase  IGF1R  insulin growth factor 1 receptor  LDH  lactate dehydrogenase  MDA  Muscular Dystrophy Association  MMP  Matrix Metallopeptidase  MRP1  multidrug resistance-associated protein 1  mTOR  mammalian target of rapamycin  MTX  methotrexate  NCCN  National Comprehensive Cancer Network  OS  overall survival  pCR  Pathologic Complete Response  PDGFR  platelet-derived growth factor receptors  PFS  progression-free survival  PKA  protein kinase A  PR  progesterone receptor  RFS  relapse-free survival  SOD  superoxide dismutase  TAM  tamoxifen  TCA  tricarboxlic acid  TS  thymidylate synthase  Combination  Mechanisms  Metformin  Chemotherapeutic drugs  

CVD  cardiovascular disease  ACE  angiotensin converting enzyme  Ang II  angiotensin II  LSW  Leu-Ser-Trp  VSMC  vascular smooth muscle cell  IRW  Ile-Arg-Trp  COX-2  cyclooxygenase 2  iNOS  inducible nitric oxide synthase  AT1R  angiotensin type I receptor  ERK1/2  extracellular signal regulated kinases 1 and 2  ROS  reactive oxygen species  DHE  dihydroethidium  IQW  Ile-Gln-Trp  Soy protein  ACE-inhibitory peptide  LSW  VSMC  Inflammation