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期刊论文 [211]
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2017 [231]
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pharmacolo... [2]
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Discovery and development of pyrotinib: A novel irreversible EGFR/HER2 dual tyrosine kinase inhibitor with favorable safety profiles for the treatment of breast cancer
期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 110, 页码: 51-61
作者:
Li, Xin
;
Yang, Changyong
;
Wan, Hong
;
Zhang, Ge
;
Feng, Jun
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2019/01/08
Pyrotinib
HER2-postive breast cancer
Irreversible EGFR/HER2 dual tyrosine kinase
inhibitor
Preclinical
Clinical
Safety
Drug metabolism
Dissolving Microneedles Integrated With Liquid Crystals Facilitate Transdermal Delivery of Sinomenine Hydrochloride
期刊论文
JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 卷号: 106, 期号: 12, 页码: 3548-3555
作者:
Gui, Zhiping
;
Wu, Xingxing
;
Wang, Shuyan
;
Cao, Yingji
;
Wan, Jun
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  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
microarray
transdermal drug delivery
skin
permeability
pharmacokinetics
biocompatibility
Critical Role of Hepatic Cyp450 sin the Testis-Specific Toxicity of (5R)-5-Hydroxytriptolide in C57BL/6 Mice
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Yu, Cunzhi
;
Li, Yu
;
Liu, Mingxia
;
Gao, Man
;
Li, Chenggang
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  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
(5R)-5-hydroxytriptolide
functional knockout
cytochrome P450
testes
gamma-H2AX
RNA polymerase II
androgen receptor
Arylacetamide Deacetylase Is Involved in Vicagrel Bioactivation in Humans
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Jiang, Jinfang
;
Chen, Xiaoyan
;
Zhong, Dafang
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  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
arylacetamide deacetylase
vicagrel
clopidogrel
hydrolytic metabolism
Radiolabeled, Antibody-Conjugated Manganese Oxide Nanoparticles for Tumor Vasculature Targeted Positron Emission Tomography and Magnetic Resonance Imaging
期刊论文
ACS APPLIED MATERIALS & INTERFACES, 2017, 卷号: 9, 期号: 44, 页码: 38304-38312
作者:
Zhan, Yonghua
;
Shi, Sixiang
;
Ehlerding, Emily B.
;
Graves, Stephen A.
;
Goel, Shreya
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  |  
浏览/下载:43/0
  |  
提交时间:2018/10/10
Manganese Oxide Nanoparticles
Cancer
Positron Emission Tomography (Pet)
Magnetic Resonance Imaging (Mri)
Cd105 (Endoglin)
Structure, physicochemical properties and pharmacokinetics of resveratrol and piperine cocrystals
期刊论文
CRYSTENGCOMM, 2017, 卷号: 19, 期号: 41, 页码: 6154-6163
作者:
He, Hongyan
;
Zhang, Qi
;
Wang, Jian-Rong
;
Mei, Xuefeng
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  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Characterization, Quantification and Pharmacokinetic Analysis of Bevacizumab and Its Glycosylation by Mass Spectrometry
期刊论文
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2017, 卷号: 45, 期号: 11, 页码: 1678-1685
作者:
Ye Ming-Liang
;
Zou Han-Fa
;
Cong Yu-Ting
;
Hu Liang-Hai
;
Gu Jing-Kai
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/06/20
Bevacizumab
Glycosylation
Liquid Chromatography-tandem Mass Spectrometry
Parallel Reaction
Monitoring
Pharmacokinetics
Albumin Binding Domain Fusing R/K-X-X-R/K Sequence for Enhancing Tumor Delivery of Doxorubicin
期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 11, 页码: 3739-3749
作者:
Liu, Liping
;
Zhang, Chun
;
Li, Zenglan
;
Wang, Chunyue
;
Bi, Jingxiu
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2017/12/20
Albumin Binding Domain
Rgdk
Rparpar
Doxorubicin
Peptide-drug Conjugate
Safety, Pharmacokinetics and Pharmacodynamics of Hetrombopag Olamine, a Novel TPO-R Agonist, in Healthy Individuals
期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2017, 卷号: 121, 期号: 5, 页码: 414-422
作者:
Zheng, Li
;
Liang, Mao-zhi
;
Zeng, Xiao-ling
;
Li, Cai-zheng
;
Zhang, Yi-fan
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  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control
期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7
作者:
Tang, Yubo
;
Tang, Feng
;
Yang, Yang
;
Zhao, Lei
;
Zhou, Hu
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  |  
浏览/下载:57/0
  |  
提交时间:2019/01/08
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