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浏览/检索结果: 共5条，第1-5条 帮助 限定条件 发表日期：2017     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, synthesis and biological evaluation of uncharged catechol derivatives as selective inhibitors of PTP1B 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 348-359 作者:  Li, Xiang-Qian;  Xu, Qi;  Luo, Jiao;  Wang, Li-Jun;  Jiang, Bo 收藏  |  浏览/下载：24/0  |  提交时间：2017/10/09 Type 2 Diabetes  Ptp1b Inhibition  Selectivity  Competitive  Cellular Activity   Effect of Wnt Signaling on the Differentiation of Islet ß-cells from Adipose-Derived Stem Cells 期刊论文 BioMed Research International, 2017 作者:  Xiao Wang;  Hefei Wang;  Yu Ren;  Xiao Hu;  Min Ma 收藏  |  浏览/下载：16/0  |  提交时间：2018/02/02 Downregulation of miR-139-5p contributes to the antiapoptotic effect of liraglutide on the diabetic rat pancreas and INS-1 cells by targeting IRS1 期刊论文 PLOS ONE, 2017, 卷号: 12 作者:  Li, Jin[1];  Su, Lei[1];  Gong, Ying-ying[1];  Ding, Mei-lin[1];  Hong, Shu-bin[2] 收藏  |  浏览/下载：3/0  |  提交时间：2019/04/24 Insulin resistance in Alzheimer's disease (AD) mouse intestinal macrophages is mediated by activation of JNK 期刊论文 EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2017, 卷号: 21, 期号: 8, 页码: 1787-1794 作者:  Zhou, Y. -L.;  Du, Y. -F.;  Du, H.;  Shao, P. 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/11 Insulin resistance  Alzheimer's disease  Macrophage  IRS1  JNK   Novel all-hydrocarbon stapled p110 alpha[E545K] peptides as blockers of the oncogenic p110 alpha[E545K]-IRS1 interaction 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2017, 卷号: 27, 期号: 24, 页码: 5446-5449 作者:  Hu, Xiao[1];  He, Yanhua[2];  Wu, Liping[3];  Hao, Yujun[4];  Wang, Zhenghe[5] 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/24 Protein-protein interaction  p110 alpha[E545K]  IRS1  Stapled peptide  % alpha-helicity  Proteolytic stability  AKT phosphorylation  Anti-cancer therapeutic