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浏览/检索结果: 共20条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270 作者:  Zhang, Wei-yao;  Lu, Wen-chao;  Jiang, Hao;  Lv, Zheng-bing;  Xie, Yi-qian 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 epigenetics  molecular docking  PRMT1  scaffold hopping  small-molecule inhibitor   Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464 作者:  Zhou, Shengbin;  Duan, Yanan;  Wang, Jiang;  Zhang, Jin;  Sun, Haifeng 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Tetrahydroberberine  4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines  Mitochondrial respiration  AMPK indirect activators  db/db mice   Remote Loading of Small-Molecule Therapeutics into Cholesterol-Enriched Cell-Membrane-Derived Vesicles 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 卷号: 56, 期号: 45, 页码: 14075-14079 作者:  Zhang, Xinxin;  Angsantikul, Pavimol;  Ying, Man;  Zhuang, Jia;  Zhang, Qiangzhe 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 biocompatibility  biomimetic nanotechnology  cell membrane  drug delivery  remote loading   Aspirin Inhibits Cancer Metastasis and Angiogenesis via Targeting Heparanase 期刊论文 CLINICAL CANCER RESEARCH, 2017, 卷号: 23, 期号: 20, 页码: 6267-6278 作者:  Dai, Xiaoyang;  Yan, Juan;  Fu, Xuhong;  Pan, Qiuming;  Sun, Danni 收藏  |  浏览/下载：34/0  |  提交时间：2019/01/08 Crystal structure determination of a chimeric FabF by XRD 期刊论文 NUCLEAR SCIENCE AND TECHNIQUES, 2017, 卷号: 28, 期号: 9 作者:  Li, Ke;  Li, Li;  Xu, Ye-Chun 收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 FabF  Chimera  X-ray diffraction  Crystal structure determination   Design, Synthesis, and Pharmacological Evaluation of Novel Multisubstituted Pyridin-3-amine Derivatives as Multitargeted Protein Kinase Inhibitors for the Treatment of Non-Small Cell Lung Cancer 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 14, 页码: 6018-6035 作者:  Zhu, Wei;  Chen, Hui;  Wang, Yulan;  Wang, Jiang;  Peng, Xia 收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 Machine-Learning-Assisted Approach for Discovering Novel Inhibitors Targeting Bromodomain-Containing Protein 4 期刊论文 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2017, 卷号: 57, 期号: 7, 页码: 1677-1690 作者:  Xing, Jing;  Lu, Wenchao;  Liu, Rongfeng;  Wang, Yulan;  Xie, Yiqian 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Underestimated Halogen Bonds Forming with Protein Backbone in Protein Data Bank 期刊论文 JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2017, 卷号: 57, 期号: 7, 页码: 1529-1534 作者:  Zhang, Qian;  Xu, Zhijian;  Shi, Jiye;  Zhu, Weiliang 收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist RevealsMechanisms of Chemokine Recognition and Molecular Mimicry by HIV 期刊论文 IMMUNITY, 2017, 卷号: 46, 期号: 6, 页码: 1005-+ 作者:  Zheng, Yi;  Han, Gye Won;  Abagyan, Ruben;  Wu, Beili;  Stevens, Raymond C. 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Gorge Motions of Acetylcholinesterase Revealed by Microsecond Molecular Dynamics Simulations 期刊论文 SCIENTIFIC REPORTS, 2017, 卷号: 7 作者:  Cheng, Shanmei;  Song, Wanling;  Yuan, Xiaojing;  Xu, Yechun 收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08