QQ客服 官方微博 反馈留言

浏览/检索结果: 共52条，第1-10条 帮助 限定条件 发表日期：2017    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Pyrrolidine Dithiocarbamate (PDTC) Attenuates Cancer Cachexia by Affecting Muscle Atrophy and Fat Lipolysis 期刊论文 FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8 作者:  Miao, Chunxiao;  Lv, Yuanyuan;  Zhang, Wanli;  Chai, Xiaoping;  Feng, Lixing 收藏  |  浏览/下载：56/0  |  提交时间：2019/01/08 cancer cachexia  PDTC  C2C12 myotubes  3T3-L1 adipocytes  muscle atrophy  fat lipolysis   Synthesis and biological evaluation of novel 4,5-bisindolyl-1,2,4-triazol-3-ones as glycogen synthase kinase-3 beta inhibitors and neuroprotective agents 期刊论文 PHARMAZIE, 2017, 卷号: 72, 期号: 12, 页码: 707-713 作者:  Hu, Yuanyuan;  Ruan, Wenchen;  Gao, Anhui;  Zhou, Yubo;  Gao, Lixin 收藏  |  浏览/下载：28/0  |  提交时间：2019/01/08 Conformation and dynamics of the C-terminal region in human phosphoglycerate mutase 1 期刊论文 ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 12, 页码: 1673-1682 作者:  Liu, Shi-en;  Hu, Jun-chi;  Zhang, Hao;  Xu, Pan;  Wan, Wei 收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 phosphoglycerate mutase 1 (PGAM1)  human cancers  metabolic target  C-terminal region  conformational changes  molecular dynamics simulation   Ancient hybridization and strong adaptation to viruses across African vervet monkey populations 期刊论文 NATURE GENETICS, 2017, 卷号: 49, 期号: 12, 页码: 1705-+ 作者:  Svardal, Hannes;  Jasinska, Anna J.;  Apetrei, Cristian;  Coppola, Giovanni;  Huang, Yu 收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate 期刊论文 NATURE GENETICS, 2017, 卷号: 49, 期号: 12, 页码: 1714-+ 作者:  Jasinska, Anna J.;  Zelaya, Ivette;  Service, Susan K.;  Peterson, Christine B.;  Cantor, Rita M. 收藏  |  浏览/下载：48/0  |  提交时间：2019/01/08 Dual-Targeting to Cancer Cells and M2 Macrophages via Biomimetic Delivery of Mannosylated Albumin Nanoparticles for Drug-Resistant Cancer Therapy 期刊论文 ADVANCED FUNCTIONAL MATERIALS, 2017, 卷号: 27, 期号: 44 作者:  Zhao, Pengfei;  Yin, Weimin;  Wu, Aihua;  Tang, Yisi;  Wang, Jinyu 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 albumin nanoparticles  combination therapy  mannose receptors  multidrug resistance  SPARC   Critical Role of Hepatic Cyp450 sin the Testis-Specific Toxicity of (5R)-5-Hydroxytriptolide in C57BL/6 Mice 期刊论文 FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8 作者:  Yu, Cunzhi;  Li, Yu;  Liu, Mingxia;  Gao, Man;  Li, Chenggang 收藏  |  浏览/下载：43/0  |  提交时间：2019/01/08 (5R)-5-hydroxytriptolide  functional knockout  cytochrome P450  testes  gamma-H2AX  RNA polymerase II  androgen receptor   Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464 作者:  Zhou, Shengbin;  Duan, Yanan;  Wang, Jiang;  Zhang, Jin;  Sun, Haifeng 收藏  |  浏览/下载：35/0  |  提交时间：2019/01/08 Tetrahydroberberine  4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines  Mitochondrial respiration  AMPK indirect activators  db/db mice   Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527 作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang 收藏  |  浏览/下载：57/0  |  提交时间：2019/01/08 Epidermal growth factor receptor  Tyrosine kinase inhibitors  Non-small cell lung cancer  T790M  Mutant-selective   Remote Loading of Small-Molecule Therapeutics into Cholesterol-Enriched Cell-Membrane-Derived Vesicles 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 卷号: 56, 期号: 45, 页码: 14075-14079 作者:  Zhang, Xinxin;  Angsantikul, Pavimol;  Ying, Man;  Zhuang, Jia;  Zhang, Qiangzhe 收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 biocompatibility  biomimetic nanotechnology  cell membrane  drug delivery  remote loading