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CORC

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OL3, a novel low-absorbed TGR5 agonist with reduced side effects, lowered blood glucose via dual actions on TGR5 activation and DPP-4 inhibition 期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 10, 页码: 1359-1369
作者:  Ma, Shan-yao;  Ning, Meng-meng;  Zou, Qing-an;  Feng, Ying;  Ye, Yang-liang
收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08
Low molecular weight fucoidan protects renal tubular cells from injury induced by albumin overload 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:  Jia, Yingli;  Sun, Yi;  Weng, Lin;  Li, Yingjie;  Zhang, Quanbin
收藏  |  浏览/下载：19/0  |  提交时间：2016/12/05
基于丝裂霉素C-磷脂复合物的新型纳米靶向载药系统的构建及性能评价 学位论文
2016, 2015
李阳
收藏  |  浏览/下载：3/0  |  提交时间：2017/06/20
A poly(amidoamine) dendrimer-based nanocarrier conjugated with Angiopep-2 for dual-targeting function in treating glioma cells 期刊论文
POLYMER CHEMISTRY, 2016
Xu, Zejun; Wang, Yao; Ma, Zhiyong; Wang, Zhijian; Wei, Yen; Jia, Xinru
收藏  |  浏览/下载：5/0  |  提交时间：2017/12/03
Implications for blood-brain-barrier permeability, in vitro oxidative stress and neurotoxicity potential induced by mesoporous silica nanoparticles: effects of surface modification 期刊论文
RSC ADVANCES, 2016
Zhou, Ming; Xie, Linlin; Fang, Chen-Jie; Yang, Hua; Wang, Yan-Jie; Zhen, Xiao-Yu; Yan, Chun-Hua; Wang, Yuji; Zhao, Ming; Peng, Shiqi
收藏  |  浏览/下载：8/0  |  提交时间：2017/12/03
Interactive Effect of the KCNJ11 Ile337Val Polymorphism and Cigarette Smoking on the Antihypertensive Response to Irbesartan in Chinese Hypertensive Patients 期刊论文
American Journal of Hypertension, 2016, 卷号: Vol.29 No.5, 页码: 553-559
作者:  Wang,Xiaobin;  Weinstock,Justin;  Xu,Xiping;  Wang,Binyan;  Hsu,Yi-Hsiang
收藏  |  浏览/下载：6/0  |  提交时间：2019/04/22
Application of a Disposable Doxorubicin Sensor for Direct Determination of Clinical Drug Concentration in Patient Blood 期刊论文
INTERNATIONAL JOURNAL OF ELECTROCHEMICAL SCIENCE, 2016, 卷号: 11, 期号: 7
作者:  Peng, Anlin;  Xu, Huilin;  Luo, Caikui;  Ding, Hong
收藏  |  浏览/下载：7/0  |  提交时间：2019/12/05
The anti-dementia drug candidate, (-)-clausenamide, improves memory impairment through its multi-target effect 期刊论文
Pharmacology and Therapeutics, 2016, 卷号: 162, 页码: 179-187
作者:  Chu, Shifeng;  Liu, Shaolin;  Duan, Wenzhen;  Cheng, Yong;  Jiang, Xueying
收藏  |  浏览/下载：9/0  |  提交时间：2019/12/27
Chirality  Clausenamide  Dementia  Long-term potentiation  Signaling pathway  Calcium  6-OHDA  6-hydroxyldopamine  ACE  acetylcholinesterase  ACh  acetylcholine  AD  Alzheimer's disease  AUC0–12 h  0–12 h area under curve  APP  amyloid precursor protein  APV  R-2-amino-5-phosphonopentanoate  AUC0−∝  whole area under curve  BBB  blood–brain barrier  BDNF  brain-derived neurotrophic factor  CaM  calmodulin  CaMKII  calmodulin kinase II  ChAT  choline acetyltransferase  CREB  cAMP responding element binding  CHM  Chinese herbal medicine  clau  clausenamide  CL  clearance  Cmax  maximum concentration  CDK-5  cyclin-dependent kinase-5  DM  diabetes mellitus  DAG  diacylglycerol  ER  endoplasmic reticulum  ERK  extracellular signal-regulated kinases  GSK-3  glycogen synthase kinase-3  IP3  inositol triphosphate  LTP  long term potentiation  MWM  Morris water maze  NGF  nerve growth factor  NMDA  N-Methyl-D-aspartate  D  nNOS  neural nitric oxide synthase  PAT  passive avoidance tasks  Pir  piracetam  PLC  phospholipase C  PP1  phosphate 1  PKC  protein kinase C  tmax  time of peak concentration  t1/2α  absorption half-life  t1/2β  elimination half-life  Tau  microtubule-associated proteins  TCM  traditional Chinese medicine  Vd  apparent volume of distribution  VDCC  voltage-dependent calcium channel  

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