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浏览/检索结果: 共11条，第1-10条 帮助 限定条件 发表日期：2016    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Preclinical Efficacy and Safety Assessment of Artemisinin-Chemotherapeutic Agent Conjugates for Ovarian Cancer 期刊论文 EBIOMEDICINE, 2016, 卷号: 14, 页码: 44-54 作者:  Li, Xiaoguang;  Zhou, Yu;  Liu, Yanling;  Zhang, Xu;  Chen, Tao 收藏  |  浏览/下载：31/0  |  提交时间：2019/01/08 Dihydroartemisinin  Drug conjugates  Cell cycle  Apoptosis  Metastasis  Ovarian cancer   Estimation of elimination half-lives of organic chemicals in humans using gradient boosting machine 期刊论文 BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2016, 卷号: 1860, 期号: 11, 页码: 2664-2671 作者:   收藏  |  浏览/下载：16/0  |  提交时间：2019/01/08 Elimination half-life  Gradient boosting machine  Applicability domain  Consensus model   Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective alpha(1A)-Adrenoceptor Antagonists 期刊论文 JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 20, 页码: 9489-9502 作者:  Guo, Diliang;  Li, Jing;  Lin, Henry;  Zhou, Yu;  Chen, Ying 收藏  |  浏览/下载：30/0  |  提交时间：2019/01/08 Metabolic characterization of pyrotinib in humans by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry 期刊论文 JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1033, 页码: 117-127 作者:  Zhu, Yunting;  Li, Liang;  Zhang, Ge;  Wan, Hong;  Yang, Changyong 收藏  |  浏览/下载：18/0  |  提交时间：2019/01/08 Pyrotinib  UPLC/Q-TOF MS  Metabolism  Human  CYP3A4  Drug-drug interaction   Valuable model for clinical trail-System Toxicological Studies on Active Components in derivatives of Lei-Gong-Teng from Traditional Chinese Medicines 会议论文 作者:  Ren J(任进) 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 Valuable model for clinical trail-System Toxicological Studies on Active Components in derivatives of Lei-Gong-Teng from Traditional Chinese Medicines   Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives 期刊论文 MOLECULES, 2016, 卷号: 21, 期号: 9 作者:  Liu, Guan-Nan;  Luo, Rong-Hua;  Zhou, Yu;  Zhang, Xing-Jie;  Li, Jian 收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 anti-HIV-1  integrase  synthesis  SAR  AIDS   Design, synthesis and biological evaluation of biphenylurea derivatives as VEGFR-2 kinase inhibitors (II) 期刊论文 CHINESE CHEMICAL LETTERS, 2016, 卷号: 27, 期号: 2, 页码: 200-204 作者:  Gao, Guo-Rui;  Li, Meng-Yuan;  Lv, Yong-Cong;  Cao, Su-Fen;  Tong, Lin-Jiang 收藏  |  浏览/下载：12/0  |  提交时间：2019/01/08 Angiogenesis  Kinase  Inhibitor  VEGFR-2   Safety evaluation of repeated intravenous infusion of sinoporphyrin with and without PDT in rats 期刊论文 PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, 2016, 卷号: 15, 期号: 11, 页码: 1366-1376 作者:  Shi, Rui;  Lin, Xiaoqi;  Zhang, Jingxuan;  Jin, Hongtao;  Wang, Aiping 收藏  |  浏览/下载：19/0  |  提交时间：2019/01/08 Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase 期刊论文 ACTA PHARMACEUTICA SINICA B, 2016, 卷号: 6, 期号: 1, 页码: 32-45 作者:  Zhou, Yu;  Liu, Jun;  Zheng, Mingyue;  Zheng, Shuli;  Jiang, Chunyi 收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 5-Lipoxygenase  5-LOX inhibitors  Pyrazole derivatives  Leukotrienes-related diseases  In vivo  Benzo-fuse heterocyle  Ischemic incults  Brain inflammation   Structural optimization and biological evaluation of l,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase 期刊论文 Acta Pharmaceutica Sinica B, 2016, 卷号: 6, 期号: 1, 页码: 32 作者:  Zhou Yu;  Liu Jun;  Zheng Mingyue;  Zheng Shuli;  Jiang Chunyi 收藏  |  浏览/下载：20/0  |  提交时间：2020/12/24 5-Lipoxygenase  5-LOX inhibitors  Pyrazole derivatives  Leukotrienes-related diseases  In vivo  Benzo-fused heterocycle  Ischemic incults  Brain inflammation