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科研机构
上海药物研究所 [52]
内容类型
期刊论文 [52]
发表日期
2016 [52]
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共52条,第1-10条
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发表日期:2016
专题:上海药物研究所
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Functional human induced hepatocytes (hiHeps) with bile acid synthesis and transport capacities: A novel in vitro cholestatic model
期刊论文
Scientific Reports, 2016, 卷号: 6
作者:
Ni, Xuan
;
Gao, Yimeng
;
Wu, Zhitao
;
Ma, Leilei
;
Chen, Chen
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/01/08
Staurosporine as an agonist for induction of GLUT4 translocation, identified by a pH-sensitive fluorescent IRAP-mOrange2 probe
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 卷号: 480, 期号: 4, 页码: 534-538
作者:
Li, Yufeng
;
Zheng, Li
;
Wang, Dan
;
Zhang, Xiang
;
Li, Jia
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
Diabetes
pH-sensitive fluorescent probe
GLUT4 translocation
Staurosporine
Insulin additive analogue
Acetylcholinesterase-independent protective effects of huperzine A against iron overload-induced oxidative damage and aberrant iron metabolism signaling in rat cortical neurons
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 11, 页码: 1391-1400
作者:
Tao, Ling-xue
;
Huang, Xiao-tian
;
Chen, Yu-ting
;
Tang, Xi-can
;
Zhang, Hai-yan
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
Alzheimer's disease
huperzine A
iron
reactive oxygen species
mitochondria dysfunction
acetylcholinesterase
Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective alpha(1A)-Adrenoceptor Antagonists
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 59, 期号: 20, 页码: 9489-9502
作者:
Guo, Diliang
;
Li, Jing
;
Lin, Henry
;
Zhou, Yu
;
Chen, Ying
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Senkyunolide I attenuates oxygen-glucose deprivation/reoxygenation-induced inflammation in microglial cells
期刊论文
BRAIN RESEARCH, 2016, 卷号: 1649, 页码: 123-131
作者:
Hu, Yang-ye
;
Wang, Yuan
;
Liang, Shuang
;
Yu, Xue-li
;
Zhang, Lei
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
Senkyunolide I
Microglial cells
Oxygen-glucose deprivation/reoxygenation
TLR4/NF-kappa B pathway
HSF-1/Hsp70
Profiling and identification of metabolites of isorhynchophylline in rats by ultra high performance liquid chromatography and linear ion trap Orbitrap mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2016, 卷号: 1033, 页码: 147-156
作者:
Wang, Jianwei
;
Qi, Peng
;
Hou, Jinjun
;
Shen, Yao
;
Yan, Bingpeng
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Isorhynchophyllin
UHPLC/LTQ-Orbitrap-MS
Metabolic profile
Metabolites
Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes
期刊论文
PHARMACOLOGICAL REVIEWS, 2016, 卷号: 68, 期号: 4, 页码: 954-1013
作者:
de Graaf, Chris
;
Donnelly, Dan
;
Wootten, Denise
;
Lau, Jesper
;
Sexton, Patrick M.
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Pharmacokinetic study of harmane and its 10 metabolites in rat after intravenous and oral administration by UPLC-ESI-MS/MS
期刊论文
Pharmaceutical biology, 2016, 卷号: 54, 期号: 9, 页码: 1768-81
作者:
Li, Shuping
;
Teng, Liang
;
Liu, Wei
;
Cheng, Xuemei
;
Jiang, Bo
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 2: Influence of UGT, CYP450, P-gp, and enterobacteria and the potential interaction in Rhizoma Anemarrhenae decoction with timosaponin B2 as the major contributor
期刊论文
BIOFACTORS, 2016, 卷号: 42, 期号: 5, 页码: 545-555
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Li, Zhixiong
;
Ma, Yuanjie
;
Lian, Shan
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
mangiferin
norathyriol
pharmacokinetics
drug-drug interaction
timosaponin B2
Rhizoma Anemarrhenae
Comparative Proteomic Analysis of Buffalo Oocytes Matured in vitro Using iTRAQ Technique
期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6
作者:
Chen, Lingsheng
;
Zhai, Linhui
;
Qu, Chunfeng
;
Zhang, Chengpu
;
Li, Sheng
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
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