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科研机构
南华大学 [2]
西安交通大学 [1]
上海药物研究所 [1]
昆明植物研究所 [1]
暨南大学 [1]
复旦大学上海医学院 [1]
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期刊论文 [8]
发表日期
2015 [8]
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Cyclic helix B peptide inhibits ischemia reperfusion-induced renal fibrosis via the PI3K/Akt/FoxO3a pathway
期刊论文
Journal of Translational Medicine, 2015, 卷号: 13
作者:
Yang, Cheng
;
Cao, Ye
;
Zhang, Yi
;
Li, Long
;
Xu, Ming
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Cyclic helix B peptide
Renal ischemia reperfusion injury
Fibrosis
Akt
FoxO3
The role of targeting kinase activity by natural products in cancer chemoprevention and chemotherapy (Review)
期刊论文
ONCOLOGY REPORTS, 2015, 卷号: 34, 期号: 2, 页码: 547-554
作者:
Luo, Xiangjian
;
Yu, Xinfang
;
Liu, Sufang
;
Deng, Qipan
;
Liu, Xiaolan
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  |  
浏览/下载:35/0
  |  
提交时间:2015/12/17
natural products
grifolin
neoalbaconol
epigallocatechin-3-gallate
cancer prevention
MiR-138 suppresses airway smooth muscle cell proliferation through the PI3K/AKT signaling pathway by targeting PDK1
期刊论文
EXPERIMENTAL LUNG RESEARCH, 2015, 卷号: 41, 期号: [db:dc_citation_issue], 页码: 363-369
作者:
Liu, Yun
;
Yang, Kunzheng
;
Sun, Xiuzhen
;
Fang, Ping
;
Shi, Hongyang
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  |  
浏览/下载:8/0
  |  
提交时间:2019/12/02
3-phosphoinositide-dependent protein kinase-1 (PDK1)
phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) signaling pathway
miR-138
airway smooth muscle cells (ASMCs)
Expression of 3-phosphoinositide-dependent protein kinase 1 in colorectal cancer as a potential therapeutic target
期刊论文
2015, 卷号: 32, 期号: 7
作者:
Xu, Zhenglei[1]
;
Liao, Bihong[2]
;
Zhang, Ru[1]
;
Yao, Jun[1]
;
Shi, Ruiyue[1]
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/10
PDK1 induces JunB, EMT, cell migration and invasion in human gallbladder cancer
期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 30
作者:
Lian, Shixian
;
Shao, Yebo
;
Liu, Houbao
;
He, Junyi
;
Lu, Weiqi
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  |  
浏览/下载:6/0
  |  
提交时间:2019/12/13
3-phosphoinositide-dependent protein kinase 1
JunB
invasion
migration
epithelial-mesenchymal transition
Phosphoinositide-dependent kinase 1 regulates leukemia stem cell maintenance in MLL-AF9-induced murine acute myeloid leukemia
期刊论文
2015, 卷号: 459, 期号: 4, 页码: 692-698
作者:
Hu, Tianyuan
;
Li, Cong
;
Zhang, Yingchi
;
Wang, Le
;
Peng, Luyun
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/13
PDK1
Akt
MLL-AF9
AML
LSCs
Apoptosis
PI3K/Akt signaling in osteosarcoma
期刊论文
Clinica Chimica Acta, 2015, 卷号: 444, 期号: Volume 444, 页码: 182-192
作者:
Zhang, Jian
;
Yu, Xiao-Hua
;
Yan, Yi-Guo
;
Wang, Cheng
;
Wang, Wen-Jun*
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  |  
浏览/下载:13/0
  |  
提交时间:2019/12/27
OS
osteosarcoma
PI3K
phosphatidylinositol 3-kinase
PTEN
phosphatase and tensin homolog
mTOR
mammalian target of rapamycin
RTKs
receptor tyrosine kinases
PDGFR
platelet-derived growth factor receptor
IGF1R
insulin-like growth factor 1 receptor
PIP2
phosphatidylinositol 4,5-biphosphate
PIP3
phosphatidylinositol 3,4,5-triphosphate
PDK1
phosphoinositide-dependent kinase 1
PH
pleckstrin homology
CDK
cyclin-dependent kinase
NF-κB
nuclear factor-κB
MDM2
Murine double minute 2
Rb
retinoblastoma
CSCs
cancer stem cells
CXCR7
CXC chemokine receptor 7
GA
gallic acid
miRNAs
microRNAs
TNF
tumor necrosis factor
HIF-1
hypoxia-inducible factor-1
ET-1
endothelin-1
ETAR
endothelin A receptor
MMP
matrix metalloproteinase.
OS
PI3K
Akt
PTEN
mTOR
MicroRNAs: New players in intervertebral disc degeneration
期刊论文
Clinica Chimica Acta, 2015, 卷号: 450, 页码: 333-341
作者:
Wang, Cheng
;
Wang, Wen-Jun
;
Yan, Yi-Guo
;
Xiang, Yong-Xiao
;
Zhang, Jian
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2019/12/27
IVD
intervertebral disc
NP
nucleus pulposus
AF
annulus fibrosus
CEPs
cartilaginous endplates
IDD
intervertebral disc degeneration
ECM
extracellular matrix
miRNAs
microRNAs
RNA pol
RNA polymerase
DGCR8
DiGeorge syndrome critical gene 8
Exp 5
exportin 5
TRBP
transactivating response RNA-binding protein
RISC
RNA-induced silencing complex
Ago
Argonaute
PI3K
phosphoinositide 3-kinase
MAPK
mitogen-activated protein kinase
TGF-β
transforming growth factor-β
PDGF
platelet-derived growth factor
IGF
insulin-like growth factor
EGF
epidermal growth factor
CDKI1B
cyclin-dependent kinase inhibitor 1B
TNF-α
tumor necrosis factor-α
FADD
Fas-associated death domain-containing protein
Col II
type II collagen
Col I
type I collagen
MMPs
matrix metalloproteinases
ADAMTSs
a disintegrin and metalloprotease with thrombospondin motifs
Col I
type I collagen
Col II
type II collagen
FGF2
fibroblast growth factor 2
FGFR
fibroblast growth factor receptor
IL-1β
interleukin-1β
NGF
nerve growth factor
HOXD10
homeobox D10
MiRNAs
IDD
NP cells
Apoptosis
Cell proliferation
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