Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance

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	Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance
	Zhu, Shaoli 1; Du, ChunLei 1; Fu, Yongqi 2; Deng, Qiling 1; Shi, Lifang 1
刊名	PLASMONICS
	2009-06-01
卷号	4 期号:2 页码:135-140
关键词	LSPR ADDLs Anti-ADDL Passivation Cr adhesion layer
英文摘要	A Cr adhesion layer inserted between Ag nanoparticles and a glass substrate, for the purpose of improving the adhesion of Ag nanoparticles to glass, was observed to cause an abnormal peak shift of extinction spectra in non-specific reactions. The undesired peak shift misleads molecule detection in non-specific reactions. To solve this issue, a practical technique using n-propyl-trimethoxysilane-based passivation for the detection of amyloid-derived diffusible ligands was investigated as a route to eliminate the abnormal peak shifting observed in the non-specific reactions. To evaluate this passivation technique, localized surface plasmon resonance immunoassay experiments were conducted. Experimental results derived with and without the passivation process were investigated as a basis for comparative analysis. Our experimental results demonstrate that this passivation technique effectively eliminates the observed peak shift originating from the Cr adhesion layer.
WOS标题词	Science & Technology ; Physical Sciences ; Technology
类目[WOS]	Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary
研究领域[WOS]	Chemistry ; Science & Technology - Other Topics ; Materials Science
关键词[WOS]	NANOSCALE OPTICAL BIOSENSOR ; SELF-ASSEMBLED MONOLAYERS ; ALZHEIMERS-DISEASE ; SILVER NANOPARTICLES ; SPECTROSCOPY ; A-BETA(1-42) ; NEUROTOXINS ; DEPENDENCE ; OLIGOMERS
收录类别	SCI
语种	英语
WOS记录号	WOS:000266390000007
公开日期	2015-12-24
内容类型	期刊论文
源URL	[http://ir.ioe.ac.cn/handle/181551/3292]
专题	光电技术研究所_光电技术研究所被WoS收录文章
作者单位	1.Chinese Acad Sci, Inst Opt & Elect, State Key Lab Opt Technol Microfabricat, Chengdu 610209, Peoples R China 2.Univ Elect Sci & Technol China, Sch Phys Elect, Chengdu 610054, Peoples R China
推荐引用方式 GB/T 7714	Zhu, Shaoli,Du, ChunLei,Fu, Yongqi,et al. Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance[J]. PLASMONICS,2009,4(2):135-140.
APA	Zhu, Shaoli,Du, ChunLei,Fu, Yongqi,Deng, Qiling,&Shi, Lifang.(2009).Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance.PLASMONICS,4(2),135-140.
MLA	Zhu, Shaoli,et al."Influence of Cr Adhesion Layer on Detection of Amyloid-Derived Diffusible Ligands Based on Localized Surface Plasmon Resonance".PLASMONICS 4.2(2009):135-140.