NMR diffusion and relaxation study of drug-protein interaction

CORC > 武汉物理与数学研究所 > 中国科学院武汉物理与数学研究所 > 2011年以前论文发表（包括2011年）

	NMR diffusion and relaxation study of drug-protein interaction
	Luo, RS; Liu, ML; Mao, XA
刊名	SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
	1999-08-01
卷号	55 期号:9 页码:1897-1901
关键词	salicylate human serum albumin interaction nuclear magnetic resonance self-diffusion coefficient relaxation rates
英文摘要	In this work, NMR diffusion and relaxation measurements are applied to the study of the interaction between the anti-inflammatory drug salicylate and the human serum albumin (HSA) in solutions. The self-diffusion coefficients and the spin-lattice relaxation rates of salicylate are measured as a function of the concentration. The dissociation constant, K-d, for drug/HSA complexes and the number of binding sites, n, are evaluated. (C) 1999 Elsevier Science B.V. AU rights reserved.
WOS标题词	Science & Technology ; Technology
类目[WOS]	Spectroscopy
研究领域[WOS]	Spectroscopy
关键词[WOS]	HUMAN SERUM-ALBUMIN ; NUCLEAR-MAGNETIC-RESONANCE ; ANTIINFLAMMATORY DRUGS ; BINDING ; IBUPROFEN ; AFFINITY ; SITE ; CHROMATOGRAPHY ; SPECTROSCOPY ; ENANTIOMERS
收录类别	SCI
语种	英语
WOS记录号	WOS:000081491400019
公开日期	2015-12-01
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/8445]
专题	武汉物理与数学研究所_2011年以前论文发表（包括2011年）
作者单位	Chinese Acad Sci, Lab Magnet Resonance & Atom Mol Phys, Wuhan Inst Phys & Math, Wuhan 430071, Peoples R China
推荐引用方式 GB/T 7714	Luo, RS,Liu, ML,Mao, XA. NMR diffusion and relaxation study of drug-protein interaction[J]. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,1999,55(9):1897-1901.
APA	Luo, RS,Liu, ML,&Mao, XA.(1999).NMR diffusion and relaxation study of drug-protein interaction.SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,55(9),1897-1901.
MLA	Luo, RS,et al."NMR diffusion and relaxation study of drug-protein interaction".SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 55.9(1999):1897-1901.