The acid free asymmetric intermolecular alpha-alkylation of aldehydes in fluorinated alcohols

	The acid free asymmetric intermolecular alpha-alkylation of aldehydes in fluorinated alcohols
	Xiao, Jian 1,2; Zhao, Kai 1; Loh, Teck-Peng 1
刊名	chemical communications
	2012
卷号	48 期号:29 页码:3548-3550
英文摘要	the acid free asymmetric intermolecular alpha-alkylation of aldehydes with alcohols has been discovered using trifluoroethanol as solvent. this unprecedented system affords the enantioenriched functionalized primary alcohols (after nabh4 reduction) in high yields and good to excellent enantioselectivities with wide substrate scope in the absence of any acid additive.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, multidisciplinary
研究领域[WOS]	chemistry
关键词[WOS]	chiral ferrocene ligands ; organic-reactions ; homogeneous catalysis ; bond formations ; aqueous-media ; water ; organocatalysis ; indoles ; solvent ; pathway
收录类别	SCI ; CCR
语种	英语
WOS记录号	WOS:000301354400024
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/143162]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Nanyang Technol Univ, Sch Phys & Math Sci, Div Chem & Biol Chem, Singapore 637371, Singapore 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Xiao, Jian,Zhao, Kai,Loh, Teck-Peng. The acid free asymmetric intermolecular alpha-alkylation of aldehydes in fluorinated alcohols[J]. chemical communications,2012,48(29):3548-3550.
APA	Xiao, Jian,Zhao, Kai,&Loh, Teck-Peng.(2012).The acid free asymmetric intermolecular alpha-alkylation of aldehydes in fluorinated alcohols.chemical communications,48(29),3548-3550.
MLA	Xiao, Jian,et al."The acid free asymmetric intermolecular alpha-alkylation of aldehydes in fluorinated alcohols".chemical communications 48.29(2012):3548-3550.