Heterochiral Domain Formation in Homochiral alpha-Dipalmitoylphosphatidylcholine (DPPC) Langmuir Monolayers at the Air/Water Interface

	Heterochiral Domain Formation in Homochiral alpha-Dipalmitoylphosphatidylcholine (DPPC) Langmuir Monolayers at the Air/Water Interface
	Lin, Lu 1,2; Liu, Anan 1,2; Guo, Yuan 1
刊名	journal of physical chemistry c
	2012-07-19
卷号	116 期号:28 页码:14863-14872
英文摘要	alpha-dipalmitoylphosphatidylcholine (dppc) langmuir monolayers at the air/water interface are an important biomimetic system. previous studies using optical imaging have shown that enantiomerically pure dppc molecules form periodical homochiral domains with close packing. however, it is unclear whether the chirality of these domains is stable or dynamic. recently, we investigated the chirality of l-dppc langmuir monolayers using second-harmonic-generation linear dichroism (shg-ld). the change in the degree of chiral excess (dce) and its sign with time indicated that the chirality transformed from homochiral to heterochiral domains, with an associated change in handedness. here we propose that hydrolysis of l-dppc is responsible for the formation of the opposite chiral state. on the basis of quantum chemistry calculations and effective pair potential (epp) theory, we give a molecular explanation for this transformation. these results provide an insight into the lipid monolayers that the chiral state of domains composed of chiral lipids is dynamic.
WOS标题词	science & technology ; physical sciences ; technology
类目[WOS]	chemistry, physical ; nanoscience & nanotechnology ; materials science, multidisciplinary
研究领域[WOS]	chemistry ; science & technology - other topics ; materials science
关键词[WOS]	air-water-interface ; frequency vibrational spectroscopy ; supported lipid-bilayers ; intrinsic bending force ; phospholipid flip-flop ; amphiphilic assemblies ; molecular chirality ; helical structures ; nonlinear optics ; real-time
收录类别	SCI
语种	英语
WOS记录号	WOS:000306503200016
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/142988]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Inst Chem, State Key Lab Mol React Dynam, Beijing Natl Lab Mol Sci, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Lin, Lu,Liu, Anan,Guo, Yuan. Heterochiral Domain Formation in Homochiral alpha-Dipalmitoylphosphatidylcholine (DPPC) Langmuir Monolayers at the Air/Water Interface[J]. journal of physical chemistry c,2012,116(28):14863-14872.
APA	Lin, Lu,Liu, Anan,&Guo, Yuan.(2012).Heterochiral Domain Formation in Homochiral alpha-Dipalmitoylphosphatidylcholine (DPPC) Langmuir Monolayers at the Air/Water Interface.journal of physical chemistry c,116(28),14863-14872.
MLA	Lin, Lu,et al."Heterochiral Domain Formation in Homochiral alpha-Dipalmitoylphosphatidylcholine (DPPC) Langmuir Monolayers at the Air/Water Interface".journal of physical chemistry c 116.28(2012):14863-14872.