An enantioselective synthesis of 3-aryl-4-phosphonobutyric acid esters via Cu-catalyzed asymmetric conjugate reduction

	An enantioselective synthesis of 3-aryl-4-phosphonobutyric acid esters via Cu-catalyzed asymmetric conjugate reduction
	Guo, Wei-Lei 1,2; Hou, Chuan-Jin 1; Duan, Zheng-Chao 2; Hu, Xiang-Ping 2
刊名	tetrahedron-asymmetry
	2011-12-31
卷号	22 期号:24 页码:2161-2164
英文摘要	the asymmetric conjugate reduction of 3-aryl-4-phosphonobutenoates has been demonstrated which provides an enantioselective synthesis of optically active 3-aryl-4-phosphonobutyric acid esters. a wide range of 3-aryl-4-phosphonobutenoate derivates are reduced with high enantioselectivities (up to 94% ee) using an (s)-segphos/cu(oac)(2)center dot h2o catalyst system (1 or 5 mol %) in the presence of pmhs and t-buoh. the reduction is influenced by the steric and electronic effects of the substrates. (c) 2012 elsevier ltd. all rights reserved.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, inorganic & nuclear ; chemistry, organic ; chemistry, physical
研究领域[WOS]	chemistry
关键词[WOS]	dynamic kinetic-resolution ; bophoz-type ligand ; alpha,beta-unsaturated esters ; diastereoselective synthesis ; hydrogenation ; phosphonates ; derivatives ; inhibitors ; hydroxyphosphonates ; hydrosilylations
收录类别	SCI ; CCR
语种	英语
WOS记录号	WOS:000301892700014
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/142684]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Dalian Polytech Univ, Sch Light Ind & Chem Engn, Dalian 116034, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Guo, Wei-Lei,Hou, Chuan-Jin,Duan, Zheng-Chao,et al. An enantioselective synthesis of 3-aryl-4-phosphonobutyric acid esters via Cu-catalyzed asymmetric conjugate reduction[J]. tetrahedron-asymmetry,2011,22(24):2161-2164.
APA	Guo, Wei-Lei,Hou, Chuan-Jin,Duan, Zheng-Chao,&Hu, Xiang-Ping.(2011).An enantioselective synthesis of 3-aryl-4-phosphonobutyric acid esters via Cu-catalyzed asymmetric conjugate reduction.tetrahedron-asymmetry,22(24),2161-2164.
MLA	Guo, Wei-Lei,et al."An enantioselective synthesis of 3-aryl-4-phosphonobutyric acid esters via Cu-catalyzed asymmetric conjugate reduction".tetrahedron-asymmetry 22.24(2011):2161-2164.