An enantioselective synthesis of 3-aryl-4-phosphonobutyric acid esters via Cu-catalyzed asymmetric conjugate reduction | |
Guo, Wei-Lei1,2; Hou, Chuan-Jin1; Duan, Zheng-Chao2; Hu, Xiang-Ping2 | |
刊名 | tetrahedron-asymmetry
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2011-12-31 | |
卷号 | 22期号:24页码:2161-2164 |
英文摘要 | the asymmetric conjugate reduction of 3-aryl-4-phosphonobutenoates has been demonstrated which provides an enantioselective synthesis of optically active 3-aryl-4-phosphonobutyric acid esters. a wide range of 3-aryl-4-phosphonobutenoate derivates are reduced with high enantioselectivities (up to 94% ee) using an (s)-segphos/cu(oac)(2)center dot h2o catalyst system (1 or 5 mol %) in the presence of pmhs and t-buoh. the reduction is influenced by the steric and electronic effects of the substrates. (c) 2012 elsevier ltd. all rights reserved. |
WOS标题词 | science & technology ; physical sciences |
类目[WOS] | chemistry, inorganic & nuclear ; chemistry, organic ; chemistry, physical |
研究领域[WOS] | chemistry |
关键词[WOS] | dynamic kinetic-resolution ; bophoz-type ligand ; alpha,beta-unsaturated esters ; diastereoselective synthesis ; hydrogenation ; phosphonates ; derivatives ; inhibitors ; hydroxyphosphonates ; hydrosilylations |
收录类别 | SCI ; CCR |
语种 | 英语 |
WOS记录号 | WOS:000301892700014 |
公开日期 | 2015-11-17 |
内容类型 | 期刊论文 |
源URL | [http://159.226.238.44/handle/321008/142684] ![]() |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.Dalian Polytech Univ, Sch Light Ind & Chem Engn, Dalian 116034, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
推荐引用方式 GB/T 7714 | Guo, Wei-Lei,Hou, Chuan-Jin,Duan, Zheng-Chao,et al. An enantioselective synthesis of 3-aryl-4-phosphonobutyric acid esters via Cu-catalyzed asymmetric conjugate reduction[J]. tetrahedron-asymmetry,2011,22(24):2161-2164. |
APA | Guo, Wei-Lei,Hou, Chuan-Jin,Duan, Zheng-Chao,&Hu, Xiang-Ping.(2011).An enantioselective synthesis of 3-aryl-4-phosphonobutyric acid esters via Cu-catalyzed asymmetric conjugate reduction.tetrahedron-asymmetry,22(24),2161-2164. |
MLA | Guo, Wei-Lei,et al."An enantioselective synthesis of 3-aryl-4-phosphonobutyric acid esters via Cu-catalyzed asymmetric conjugate reduction".tetrahedron-asymmetry 22.24(2011):2161-2164. |
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