Systems Biology-Based Diagnostic Principles as Pillars of the Bridge between Chinese and Western Medicine

	Systems Biology-Based Diagnostic Principles as Pillars of the Bridge between Chinese and Western Medicine
	van der Greef, Jan 1,2,3,5; van Wietmarschen, Herman 2,3; Schroen, Jan 2; Wang, Mei 2,5; Hankemeier, Thomas 2,3; Xu, Guowang 2,4
刊名	planta medica
	2010-12-01
卷号	76 期号:17 页码:2036-2047
关键词	personalized medicine Chinese medicine diagnosis systems biology rheumatoid arthritis metabolomics phenotyping targeted care
英文摘要	innovative systems approaches to develop medicine and health care are emerging from the integration of chinese and western medicine strategies, philosophies and practices. the two medical systems are highly complementary as the reductionist aspects of western medicine are favourable in acute disease situations and the holistic aspects of chinese medicine offer more opportunities in chronic conditions and for prevention. in this article we argue that diagnosis plays a key role in building the bridge between chinese and western medicine. recent advances in the study of health, healing, placebo effects and patient-physician interactions will be discussed pointing out the development of a system-based diagnosis. especially, a system biology-based diagnosis can be used to capture phenotype information, leading towards a scientific basis for a more refined patient characterization, new diagnostic tools and personalized heath strategies. subtyping of rheumatoid arthritis patients based on chinese diagnostic principles is discussed as an example. new insights from this process of integrating western and chinese medicine will pave the way for a patient-centred health care ecosystem.
WOS标题词	science & technology ; life sciences & biomedicine
类目[WOS]	plant sciences ; chemistry, medicinal ; pharmacology & pharmacy
研究领域[WOS]	plant sciences ; pharmacology & pharmacy
关键词[WOS]	wilfordii hook-f ; rheumatoid-arthritis ; double-blind ; placebo ; disease ; metabolomics ; pharmacology ; mindfulness ; discovery ; cytokines
收录类别	SCI
语种	英语
WOS记录号	WOS:000284941000012
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/142234]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.TNO Qual Life, NL-3700 AJ Zeist, Netherlands 2.Sino Dutch Ctr Prevent & Personalized Med, Zeist, Netherlands 3.Leiden Univ, Netherlands Metabol Ctr, Div Analyt Biosci, Leiden, Netherlands 4.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian, Peoples R China 5.SU BioMed, Zeist, Netherlands
推荐引用方式 GB/T 7714	van der Greef, Jan,van Wietmarschen, Herman,Schroen, Jan,et al. Systems Biology-Based Diagnostic Principles as Pillars of the Bridge between Chinese and Western Medicine[J]. planta medica,2010,76(17):2036-2047.
APA	van der Greef, Jan,van Wietmarschen, Herman,Schroen, Jan,Wang, Mei,Hankemeier, Thomas,&Xu, Guowang.(2010).Systems Biology-Based Diagnostic Principles as Pillars of the Bridge between Chinese and Western Medicine.planta medica,76(17),2036-2047.
MLA	van der Greef, Jan,et al."Systems Biology-Based Diagnostic Principles as Pillars of the Bridge between Chinese and Western Medicine".planta medica 76.17(2010):2036-2047.