A Lanthanide-Complex-Based Ratiometric Luminescent Probe Specific for Peroxynitrite

	A Lanthanide-Complex-Based Ratiometric Luminescent Probe Specific for Peroxynitrite
	Song, Cuihong 1; Ye, Zhiqiang 2; Wang, Guilan 2; Yuan, Jingli 1,2; Guan, Yafeng 1
刊名	chemistry-a european journal
	2010
卷号	16 期号:22 页码:6464-6472
关键词	analytical methods cell imaging lanthanides luminescence peroxynitrite
英文摘要	a lanthanide-complex-based ratiometric luminescence probe specific for peroxynitrite (onoo-), 4'-(2,4-dimethoxyphenyl)-2,2':6',2 ''-terpyridine- 6,6 ''-diyl]bis(methylenenitrilo)tetrakis-(acetate)-eu3+/tb3+ ([eu3+/tb3+ (dtta)]), has been designed and synthesized. both [eu3+(dtta)] and [tb3+(dtta)] are highly water soluble with large stability constants at approximate to 10(20), and strongly luminescent with luminescence quantum yields of 10.0 and 9.9%, respectively, and long luminescence lifetimes of 1.38 and 0.26 ms, respectively. it was found that the luminescence of [tb3+(dtta)] could be quenched by onoo- rapidly and specifically in aqueous buffers, while that of [eu3+(dtta)] did not respond to the addition of onoo-. thus, by simply mixing [eu3+(dtta)] and [tb3+(dtta)] in an aqueous buffer, a ratiometric luminescence probe specific for time-gated luminescence detection of onoo- was obtained. the performance of [tb3+(dtta).] and [eu3+/tb3+(dtta)] as the probes for luminescence imaging detection of onoo- in living cells was investigated. the results demonstrated the efficacy and advantages of the new ratiometric luminescence probe for highly sensitive luminescence bioimaging application.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, multidisciplinary
研究领域[WOS]	chemistry
关键词[WOS]	singlet oxygen ; excited-states ; europium ; indicators ; oxidation ; chelate ; sensor ; cells
收录类别	SCI ; IC
语种	英语
WOS记录号	WOS:000279445400010
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/142043]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dept Instrumentat & Analyt Sci, Dalian 116023, Peoples R China 2.Dalian Univ Technol, Sch Chem, Dalian 116012, Peoples R China
推荐引用方式 GB/T 7714	Song, Cuihong,Ye, Zhiqiang,Wang, Guilan,et al. A Lanthanide-Complex-Based Ratiometric Luminescent Probe Specific for Peroxynitrite[J]. chemistry-a european journal,2010,16(22):6464-6472.
APA	Song, Cuihong,Ye, Zhiqiang,Wang, Guilan,Yuan, Jingli,&Guan, Yafeng.(2010).A Lanthanide-Complex-Based Ratiometric Luminescent Probe Specific for Peroxynitrite.chemistry-a european journal,16(22),6464-6472.
MLA	Song, Cuihong,et al."A Lanthanide-Complex-Based Ratiometric Luminescent Probe Specific for Peroxynitrite".chemistry-a european journal 16.22(2010):6464-6472.