Enantioselective Organocatalytic Michael Addition of Malonates to alpha,beta-Unsaturated Ketones

	Enantioselective Organocatalytic Michael Addition of Malonates to alpha,beta-Unsaturated Ketones
	Li, Pengfei 1,2; Wen, Shigang 2; Yu, Feng 2; Liu, Qiaoxia 2; Li, Wenjun 2; Wang, Yongcan 1; Liang, Xinmiao 1,2; Ye, Jinxing 2
刊名	organic letters
	2009-02-05
卷号	11 期号:3 页码:753-756
英文摘要	a novel type of primary amine thiourea organocatalysts derived from 1,2-diaminocyclohexane and 9-amino (9-deoxy) cinchona alkaloid was developed into asymmetric michael addition of malonates to enones. a series of cyclic and acyclic enones could react very well with different malonates in the presence of 4 with 0.5-10 mol % catalyst loading affording chiral michael adducts with excellent yields and ee values.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, organic
研究领域[WOS]	chemistry
关键词[WOS]	bifunctional cinchona organocatalysts ; baylis-hillman reaction ; conjugate addition ; asymmetric catalysis ; cyclic enones ; ionic liquids ; 1,3-dicarbonyl compounds ; alkaloid derivatives ; organic catalyst ; primary amines
收录类别	SCI ; IC ; CCR
语种	英语
WOS记录号	WOS:000262913500065
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/141487]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.E China Univ Sci & Technol, Minist Educ, Engn Res Ctr Pharmaceut Proc Chem, Shanghai 200237, Peoples R China
推荐引用方式 GB/T 7714	Li, Pengfei,Wen, Shigang,Yu, Feng,et al. Enantioselective Organocatalytic Michael Addition of Malonates to alpha,beta-Unsaturated Ketones[J]. organic letters,2009,11(3):753-756.
APA	Li, Pengfei.,Wen, Shigang.,Yu, Feng.,Liu, Qiaoxia.,Li, Wenjun.,...&Ye, Jinxing.(2009).Enantioselective Organocatalytic Michael Addition of Malonates to alpha,beta-Unsaturated Ketones.organic letters,11(3),753-756.
MLA	Li, Pengfei,et al."Enantioselective Organocatalytic Michael Addition of Malonates to alpha,beta-Unsaturated Ketones".organic letters 11.3(2009):753-756.