Selective enrichment with "click oligo (ethylene glycol)" column and TOF-MS characterization of simple phenylpropanoids in the fruits of Forsythia suspensa

	Selective enrichment with "click oligo (ethylene glycol)" column and TOF-MS characterization of simple phenylpropanoids in the fruits of Forsythia suspensa
	Wang, Yaqin 1,2; Guo, Zhimou 1; Jin, Yu 3; Zhang, Xiuli 1; Li, Wei 1; Liang, Xinmiao 1,3
刊名	journal of separation science
	2009-09-01
卷号	32 期号:17 页码:2958-2966
关键词	Click oligo (ethylene glycol) Forsythia suspensa Lignans Phenylpropanoids Selective enrichment TOF-MS
英文摘要	to separate samples of complex natural products, highly efficient and selective separation methods should be developed. herein, a selective enrichment method was developed to separate forsythia suspensa components with "click oligo (ethylene glycol)" (oeg) column in reversed phase (rp) mode. in this method, f. suspensa aqueous extract was successfully separated. and three fractions with structure-related compounds were obtained. fraction i mainly consisted of c(6)-c(2) natural alcohols and glycosides, fraction ii mostly consisted of lignans, and fraction iii mainly consisted of simple phenylpropanoids (sp). then, the three fractions were separated with ultra-performance liquid chromatography (uplc). four more lignans were observed in fraction ii, and eight more sp were observed in fraction iii than that without oeg column. fraction iii was successively characterized by tof-ms, 2 acids (caffeic acid and chlorogenetic acid), 26 sp with caffeoyl, and 26 sp with coumaroyl were characterized. the results prove that a valid method has been developed to selectively enrich sp and lignans. and the method combined with uplc can efficiently separate sp and lignans. furthermore, the tof-ms method is effective to confirm the substituents of sp.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, analytical
研究领域[WOS]	chemistry
关键词[WOS]	performance liquid-chromatography ; molecularly imprinted polymers ; solid-phase extraction ; tandem mass-spectrometry ; stationary-phase ; oligo(ethylene glycol) ; acid ; derivatives ; separation
收录类别	SCI
语种	英语
WOS记录号	WOS:000269780400014
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/141351]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Shenyang Ligong Univ, Sch Environm & Chem Engn, Shenyang, Peoples R China 3.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China
推荐引用方式 GB/T 7714	Wang, Yaqin,Guo, Zhimou,Jin, Yu,et al. Selective enrichment with "click oligo (ethylene glycol)" column and TOF-MS characterization of simple phenylpropanoids in the fruits of Forsythia suspensa[J]. journal of separation science,2009,32(17):2958-2966.
APA	Wang, Yaqin,Guo, Zhimou,Jin, Yu,Zhang, Xiuli,Li, Wei,&Liang, Xinmiao.(2009).Selective enrichment with "click oligo (ethylene glycol)" column and TOF-MS characterization of simple phenylpropanoids in the fruits of Forsythia suspensa.journal of separation science,32(17),2958-2966.
MLA	Wang, Yaqin,et al."Selective enrichment with "click oligo (ethylene glycol)" column and TOF-MS characterization of simple phenylpropanoids in the fruits of Forsythia suspensa".journal of separation science 32.17(2009):2958-2966.