Chiral 1,2,3,4-tetrahydro-1-naphthylamine-derived phosphine-phosphoramidite ligand (THNAPhos): Application in highly enantioselective hydrogenations of functionalized C=C bonds

	Chiral 1,2,3,4-tetrahydro-1-naphthylamine-derived phosphine-phosphoramidite ligand (THNAPhos): Application in highly enantioselective hydrogenations of functionalized C=C bonds
	Qiu, Min; Hu, Xiang-Ping; Wang, Dao-Yong; Deng, Jun; Huang, Jia-Di; Yu, Sai-Bo; Duan, Zheng-Chao; Zheng, Zhuo
刊名	advanced synthesis & catalysis
	2008-06-01
卷号	350 期号:9 页码:1413-1418
关键词	asymmetric catalysis hydrogenation olefins phosphine-phosphoramidite ligand
英文摘要	we have recently reported a new chiral 1,2,3,4-tetrahydro-1-naphthylamine-derived phosphine-phosphoramidite ligand, (r-c,r-a)-thnaphos, that is highly efficient in the rhodium-catalyzed asymmetric hydrogenation of a broad range of alpha-enol ester phosphonates. to further demonstrate the utility of thnaphos in asymmetric hydrogenation, in this paper, we describe its new application in the asymmetric hydrogenation of alpha-dehydroamino acid esters, enamides, dimethyl itaconate and alpha-enamido phosphonates. the results disclosed that the rh/(r-c,r-a)-thnaphos complex is highly effective for the enantioselective hydrogenation of these kinds of functionalized c=c olefins, affording the corresponding hydrogenation product in excellent enantioselectivities (normally over 99% ee).
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, applied ; chemistry, organic
研究领域[WOS]	chemistry
关键词[WOS]	catalyzed asymmetric hydrogenation ; phosphonic acid-derivatives ; alpha-amino ; micellar media ; hydroxy ; complexes ; quinaphos ; esters
收录类别	SCI
语种	英语
WOS记录号	WOS:000256976100035
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/140797]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Qiu, Min,Hu, Xiang-Ping,Wang, Dao-Yong,et al. Chiral 1,2,3,4-tetrahydro-1-naphthylamine-derived phosphine-phosphoramidite ligand (THNAPhos): Application in highly enantioselective hydrogenations of functionalized C=C bonds[J]. advanced synthesis & catalysis,2008,350(9):1413-1418.
APA	Qiu, Min.,Hu, Xiang-Ping.,Wang, Dao-Yong.,Deng, Jun.,Huang, Jia-Di.,...&Zheng, Zhuo.(2008).Chiral 1,2,3,4-tetrahydro-1-naphthylamine-derived phosphine-phosphoramidite ligand (THNAPhos): Application in highly enantioselective hydrogenations of functionalized C=C bonds.advanced synthesis & catalysis,350(9),1413-1418.
MLA	Qiu, Min,et al."Chiral 1,2,3,4-tetrahydro-1-naphthylamine-derived phosphine-phosphoramidite ligand (THNAPhos): Application in highly enantioselective hydrogenations of functionalized C=C bonds".advanced synthesis & catalysis 350.9(2008):1413-1418.