Simultaneous characterization of isoflavonoids and astragalosides in two Astragalus species by high-performance liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry

	Simultaneous characterization of isoflavonoids and astragalosides in two Astragalus species by high-performance liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry
	Zhang, Xi; Xiao, Hong-Bin; Xue, Xing-Ya; Sun, Yan-Guo; Liang, Xin-Miao
刊名	journal of separation science
	2007-08-01
卷号	30 期号:13 页码:2059-2069
关键词	astragaloside astragalus membranaceus astragalus mongholicus HPLC-APCI/MS/MS isoflavone
英文摘要	a method was developed for the simultaneous identification of astragalosides (ags) and isoflavonoids (ifs) in the roots of astragalus membranaceus and astragalus mongholicus by hplc coupled with atmospheric pressure chemical ionization ms/ms (hplc-apci-ms/ms). diagnostic fragment ions of ags and different group of ifs were obtained with one ag and eight if standards analyzed by cid-ms, which were adopted as characteristic ms/ms fingerprints for further identification of these compounds in the two astragalus species by using hplc-apci-ms/ms. a total of 20 ifs and 10 ags were identified or tentatively identified. among them, six ifs were detected in a. membranaceus for the first time and five ifs were firstly identified in a. mongholicus. the results indicate that hplc-apci-ms/ms is a powerful tool for the simultaneous characterization of ifs and ags in complex matrix.
WOS标题词	science & technology ; physical sciences
类目[WOS]	chemistry, analytical
研究领域[WOS]	chemistry
关键词[WOS]	radix-astragali ; membranaceus ; identification ; mongholicus ; aglycones ; saponins ; flavonol ; extract ; roots ; array
收录类别	SCI
语种	英语
WOS记录号	WOS:000249171200008
公开日期	2015-11-17
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/140530]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
推荐引用方式 GB/T 7714	Zhang, Xi,Xiao, Hong-Bin,Xue, Xing-Ya,et al. Simultaneous characterization of isoflavonoids and astragalosides in two Astragalus species by high-performance liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry[J]. journal of separation science,2007,30(13):2059-2069.
APA	Zhang, Xi,Xiao, Hong-Bin,Xue, Xing-Ya,Sun, Yan-Guo,&Liang, Xin-Miao.(2007).Simultaneous characterization of isoflavonoids and astragalosides in two Astragalus species by high-performance liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry.journal of separation science,30(13),2059-2069.
MLA	Zhang, Xi,et al."Simultaneous characterization of isoflavonoids and astragalosides in two Astragalus species by high-performance liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry".journal of separation science 30.13(2007):2059-2069.