(S)-ibuprofen-imprinted polymers incorporating gamma-methacryloxypropyltrimethoxysilane for CEC separation of ibuprofen enantiomers | |
Deng, Qi-Liang; Lun, Zhi-Hong; Gao, Ru-Yu; Zhang, Li-Hua; Zhang, Wei-Bing; Zhang, Yu-Kui | |
刊名 | electrophoresis |
2006-11-01 | |
卷号 | 27期号:21页码:4351-4358 |
关键词 | capillary electrochromatography chiral recognition ibuprofen molecularly imprinted polymer |
英文摘要 | in this report, a novel preparation method of molecularly imprinted polymers (mips) for cec was developed. molecularly imprinted monolithic columns for (s)-ibuprofen were prepared and evaluated, in which charged entities responsible for establishing eof have been derived from gamma-methacryloxypropyltrimethoxysilane (gamma-maps), which was hydrolyzed following copolymerization with 4-vinylpyridine (4-vpy) and ethylene glycol dimethacrylate (edma). the eof and molecular recognition of the stationary phase were investigated in aqueous and nonaqueous media, respectively. the experimental results indicated that the material showed a reasonably stable eof and the prepared separation materials were capable of separating racemic ibuprofen, a task that could not be accomplished by mips prepared in parallel, using methacrylic acid (maa) as a functional monomer. the efficiency at ph 3.2 for the first-eluted enantiomer and the last-eluted enantiomer (the imprinted analyte) were 128 700 and 2100 plates/m, respectively. |
WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
类目[WOS] | biochemical research methods ; chemistry, analytical |
研究领域[WOS] | biochemistry & molecular biology ; chemistry |
关键词[WOS] | molecularly imprinted polymers ; selective stationary phases ; capillary electrochromatography ; liquid-chromatography ; electrophoresis ; recognition ; coatings |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000242222500027 |
公开日期 | 2015-11-17 |
内容类型 | 期刊论文 |
源URL | [http://159.226.238.44/handle/321008/140130] |
专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
作者单位 | 1.Nankai Univ, State Key Lab Element Organ Chem, Inst Element Organ Chem, Tianjin 300071, Peoples R China 2.Tianjin Univ Sci & Technol, Coll Sci, Tianjin, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China |
推荐引用方式 GB/T 7714 | Deng, Qi-Liang,Lun, Zhi-Hong,Gao, Ru-Yu,et al. (S)-ibuprofen-imprinted polymers incorporating gamma-methacryloxypropyltrimethoxysilane for CEC separation of ibuprofen enantiomers[J]. electrophoresis,2006,27(21):4351-4358. |
APA | Deng, Qi-Liang,Lun, Zhi-Hong,Gao, Ru-Yu,Zhang, Li-Hua,Zhang, Wei-Bing,&Zhang, Yu-Kui.(2006).(S)-ibuprofen-imprinted polymers incorporating gamma-methacryloxypropyltrimethoxysilane for CEC separation of ibuprofen enantiomers.electrophoresis,27(21),4351-4358. |
MLA | Deng, Qi-Liang,et al."(S)-ibuprofen-imprinted polymers incorporating gamma-methacryloxypropyltrimethoxysilane for CEC separation of ibuprofen enantiomers".electrophoresis 27.21(2006):4351-4358. |
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