Screening method for determining the presence of N-nitrosodiethanolamine in cosmetics by open-tubular capillary electrochromatography

	Screening method for determining the presence of N-nitrosodiethanolamine in cosmetics by open-tubular capillary electrochromatography
	Matyska, MT ; Pesek, JJ ; Yang, L
刊名	journal of chromatography a
	2000-07-28
卷号	887 期号:1-2 页码:497-503
关键词	cosmetics electrochromatography nitrosodiethanolamine
英文摘要	the presence of the carcinogenic n-nitrosodiethanolamine (ndela; cas no. 1116-54-7) in cosmetic samples was determined using an etched, c-18 modified capillary in the open-tubular capillary electrochromatography technique. a very simple extraction procedure leads to a sample matrix free from interferences. the calibration curve was created using uv detection at 214 nn. the detector response was linear in the range of 5-120 ppm total amount injected. minimum detection limits (1 ppm ndela injected on capillary) are suitable for screening a large number of cosmetic samples. diethanolamine and triethanolamine precursors of nitrosamines are not detected at the wavelength used. cosmetic samples were analyzed unspiked and after addition of 60 ppm of ndela. in spiked samples recoveries varied from 94% (hand and body lotion) to 55% (lipstick sample). ndela was found in unspiked samples of old (5-15 years old) cosmetics at concentrations of 14.0 ppm and 35.0 ppm. (c) 2000 elsevier science b.v. all rights reserved.
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	performance liquid-chromatography ; skin in-vitro ; percutaneous penetration ; nitrosamines ; vehicles ; products
收录类别	SCI
语种	英语
WOS记录号	WOS:000088315800038
公开日期	2015-11-10
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/138802]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.San Jose State Univ, Dept Chem, San Jose, CA 95192 USA 2.Acad Sinica, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, Dalian 116011, Liaoning Provin, Peoples R China
推荐引用方式 GB/T 7714	Matyska, MT,Pesek, JJ,Yang, L. Screening method for determining the presence of N-nitrosodiethanolamine in cosmetics by open-tubular capillary electrochromatography[J]. journal of chromatography a,2000,887(1-2):497-503.
APA	Matyska, MT,Pesek, JJ,&Yang, L.(2000).Screening method for determining the presence of N-nitrosodiethanolamine in cosmetics by open-tubular capillary electrochromatography.journal of chromatography a,887(1-2),497-503.
MLA	Matyska, MT,et al."Screening method for determining the presence of N-nitrosodiethanolamine in cosmetics by open-tubular capillary electrochromatography".journal of chromatography a 887.1-2(2000):497-503.