A rapid, straightforward, and print house compatible mass fabrication method for integrating 3D paper-based microfluidics

	A rapid, straightforward, and print house compatible mass fabrication method for integrating 3D paper-based microfluidics
	Xiao, Liangpin 1,2; Liu, Xianming 1; Zhong, Runtao 1; Zhang, Kaiqing 3; Zhang, Xiaodi 3; Zhou, Xiaomian 4; Lin, Bingcheng 1; Du, Yuguang 1
刊名	electrophoresis
	2013-11-01
卷号	34 期号:20-21 页码:3003-3007
关键词	3D paper-based microfluidics Nitrite colorimetric assay Print house compatible mass fabrication Wax-printing
英文摘要	three-dimensional (3d) paper-based microfluidics, which is featured with high performance and speedy determination, promise to carry out multistep sample pretreatment and orderly chemical reaction, which have been used for medical diagnosis, cell culture, environment determination, and so on with broad market prospect. however, there are some drawbacks in the existing fabrication methods for 3d paper-based microfluidics, such as, cumbersome and time-consuming device assembly; expensive and difficult process for manufacture; contamination caused by organic reagents from their fabrication process. here, we present a simple printing-bookbinding method for mass fabricating 3d paper-based microfluidics. this approach involves two main steps: (i) wax-printing, (ii) bookbinding. we tested the delivery capability, diffusion rate, homogeneity and demonstrated the applicability of the device to chemical analysis by nitrite colorimetric assays. the described method is rapid (<30 s), cheap, easy to manipulate, and compatible with the flat stitching method that is common in a print house, making itself an ideal scheme for large-scale production of 3d paper-based microfluidics.
WOS标题词	science & technology ; life sciences & biomedicine ; physical sciences
类目[WOS]	biochemical research methods ; chemistry, analytical
研究领域[WOS]	biochemistry & molecular biology ; chemistry
关键词[WOS]	immunodevice ; device ; immunoassay ; tape
收录类别	SCI
语种	英语
WOS记录号	WOS:000330127500008
公开日期	2015-11-10
内容类型	期刊论文
源URL	[http://159.226.238.44/handle/321008/137886]
专题	大连化学物理研究所_中国科学院大连化学物理研究所
作者单位	1.Chinese Acad Sci, Dalian Inst Chem Phys, Res Ctr Lab Chip, Dalian, Peoples R China 2.Univ Chinese Acad Sci, Sch Chem & Chem Engn, Beijing, Peoples R China 3.Bioman Technol Co Ltd, Guangzhou, Guangdong, Peoples R China 4.Guangzhou Med Univ, Affiliated Hosp, Guangzhou Municipal Peoples Hosp 1, Dept Lab Med, Guangzhou, Guangdong, Peoples R China
推荐引用方式 GB/T 7714	Xiao, Liangpin,Liu, Xianming,Zhong, Runtao,et al. A rapid, straightforward, and print house compatible mass fabrication method for integrating 3D paper-based microfluidics[J]. electrophoresis,2013,34(20-21):3003-3007.
APA	Xiao, Liangpin.,Liu, Xianming.,Zhong, Runtao.,Zhang, Kaiqing.,Zhang, Xiaodi.,...&Du, Yuguang.(2013).A rapid, straightforward, and print house compatible mass fabrication method for integrating 3D paper-based microfluidics.electrophoresis,34(20-21),3003-3007.
MLA	Xiao, Liangpin,et al."A rapid, straightforward, and print house compatible mass fabrication method for integrating 3D paper-based microfluidics".electrophoresis 34.20-21(2013):3003-3007.