Analysis of perphenazine and fluphenazine by capillary electrophoresis coupled with tris (2,2 '-bipyridyl) ruthenium (II) electrochemiluminescence detection

	Analysis of perphenazine and fluphenazine by capillary electrophoresis coupled with tris (2,2 '-bipyridyl) ruthenium (II) electrochemiluminescence detection
	Xu, Lei ; Li, Libo ; Huang, Jianshe ; You,Tianyan
刊名	talanta
	2014
卷号	118 期号:1 页码:1-6
关键词	FLOW-INJECTION ELECTROCHEMILUMINESCENCE CHEMILUMINESCENCE DETERMINATION ELECTROCHEMICAL DETECTION GOLD ELECTRODE AMINO-ACIDS SEPARATION SERUM TRIS(2 SAMPLES URINE 2'-BIPYRIDYL)RUTHENIUM(III)
通讯作者	you,ty
英文摘要	the coupling of end-column tris (2,2'-bipyridyl) ruthenium (ii) electrochemiluminescence (ecl) detection with capillary electrophoresis (ce) was developed for the analysis of two antipsychotic drugs, perphenazine (pph) and fluphenazine (fph). the parameters related to ce separation and ecl detection, including the detection potential, the buffer ph value and concentration, the separation voltage, and ru(bpy)(3)(2+) concentration, were investigated in detail. under optimum conditions, pph and fph were well separated and detected within 11 min. the linear ranges were 0.1-5 mu m for pph, and 0.1-7.5 mu m for fph, respectively. the limits of detection of pph and fph were 5 and 10 nm (s/n=3). the relative standard deviations (n=3) of the ecl intensity and the migration time were less than 2.5 and 0.65% in a day, and less than 3.4 and 1.7% in different three days. the proposed method was successfully applied to determine pph and fph in spiked urine samples with satisfactory results. (c) 2013 elsevier b.v. all rights reserved.
收录类别	SCI
语种	英语
公开日期	2015-10-27
内容类型	期刊论文
源URL	[http://ir.ciac.jl.cn/handle/322003/57321]
专题	长春应用化学研究所_长春应用化学研究所知识产出_期刊论文
推荐引用方式 GB/T 7714	Xu, Lei,Li, Libo,Huang, Jianshe,et al. Analysis of perphenazine and fluphenazine by capillary electrophoresis coupled with tris (2,2 '-bipyridyl) ruthenium (II) electrochemiluminescence detection[J]. talanta,2014,118(1):1-6.
APA	Xu, Lei,Li, Libo,Huang, Jianshe,&You,Tianyan.(2014).Analysis of perphenazine and fluphenazine by capillary electrophoresis coupled with tris (2,2 '-bipyridyl) ruthenium (II) electrochemiluminescence detection.talanta,118(1),1-6.
MLA	Xu, Lei,et al."Analysis of perphenazine and fluphenazine by capillary electrophoresis coupled with tris (2,2 '-bipyridyl) ruthenium (II) electrochemiluminescence detection".talanta 118.1(2014):1-6.