A peripheral component interconnect express-based scalable and highly integrated pulsed spectrometer for solution state dynamic nuclear polarization

CORC > 武汉物理与数学研究所 > 中国科学院武汉物理与数学研究所 > 磁共振基础研究部

	A peripheral component interconnect express-based scalable and highly integrated pulsed spectrometer for solution state dynamic nuclear polarization
	He, Yugui 1,2; Feng, Jiwen 2; Zhang, Zhi 2,3; Wang, Chao 2,3; Wang, Dong 2; Chen, Fang 2; Liu, Maili 2; Liu, Chaoyang 1,2
刊名	REVIEW OF SCIENTIFIC INSTRUMENTS
	2015-08-01
卷号	86 期号:8
英文摘要	High sensitivity, high data rates, fast pulses, and accurate synchronization all represent challenges for modern nuclear magnetic resonance spectrometers, which make any expansion or adaptation of these devices to new techniques and experiments difficult. Here, we present a Peripheral Component Interconnect Express (PCIe)-based highly integrated distributed digital architecture pulsed spectrometer that is implemented with electron and nucleus double resonances and is scalable specifically for broad dynamic nuclear polarization (DNP) enhancement applications, including DNP-magnetic resonance spectroscopy/imaging (DNP-MRS/MRI). The distributed modularized architecture can implement more transceiver channels flexibly to meet a variety of MRS/MRI instrumentation needs. The proposed PCIe bus with high data rates can significantly improve data transmission efficiency and communication reliability and allow precise control of pulse sequences. An external high speed double data rate memory chip is used to store acquired data and pulse sequence elements, which greatly accelerates the execution of the pulse sequence, reduces the TR (time of repetition) interval, and improves the accuracy of TR in imaging sequences. Using clock phase-shift technology, we can produce digital pulses accurately with high timing resolution of 1 ns and narrow widths of 4 ns to control the microwave pulses required by pulsed DNP and ensure overall system synchronization. The proposed spectrometer is proved to be both feasible and reliable by observation of a maximum signal enhancement factor of approximately -170 for H-1, and a high quality water image was successfully obtained by DNP-enhanced spin-echo H-1 MRI at 0.35 T. (C) 2015 AIP Publishing LLC.
WOS标题词	Science & Technology ; Technology ; Physical Sciences
类目[WOS]	Instruments & Instrumentation ; Physics, Applied
研究领域[WOS]	Instruments & Instrumentation ; Physics
关键词[WOS]	MAGNETIC-RESONANCE ; DNP SPECTROMETER ; NMR ; 3T
收录类别	SCI
语种	英语
WOS记录号	WOS:000360648800002
公开日期	2015-10-13
内容类型	期刊论文
源URL	[http://ir.wipm.ac.cn/handle/112942/7880]
专题	武汉物理与数学研究所_磁共振基础研究部
作者单位	1.Huazhong Univ Sci & Technol, Sch Opt & Elect Informat, Wuhan Natl Lab Optoelect, Wuhan 430074, Peoples R China 2.Chinese Acad Sci, Wuhan Inst Phys & Math, State Key Lab Magnet Resonance & Atom & Mol Phys, Wuhan 430071, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100048, Peoples R China
推荐引用方式 GB/T 7714	He, Yugui,Feng, Jiwen,Zhang, Zhi,et al. A peripheral component interconnect express-based scalable and highly integrated pulsed spectrometer for solution state dynamic nuclear polarization[J]. REVIEW OF SCIENTIFIC INSTRUMENTS,2015,86(8).
APA	He, Yugui.,Feng, Jiwen.,Zhang, Zhi.,Wang, Chao.,Wang, Dong.,...&Liu, Chaoyang.(2015).A peripheral component interconnect express-based scalable and highly integrated pulsed spectrometer for solution state dynamic nuclear polarization.REVIEW OF SCIENTIFIC INSTRUMENTS,86(8).
MLA	He, Yugui,et al."A peripheral component interconnect express-based scalable and highly integrated pulsed spectrometer for solution state dynamic nuclear polarization".REVIEW OF SCIENTIFIC INSTRUMENTS 86.8(2015).