Re-visiting the nature and relationships between neurological signs and neurocognitive functions in first-episode schizophrenia: An invariance model across time

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	Re-visiting the nature and relationships between neurological signs and neurocognitive functions in first-episode schizophrenia: An invariance model across time
	Chan, Raymond C. K.1 ; Dai, Shan 2; Lui, Simon S. Y.1,3,4; Ho, Karen K. Y.3; Hung, Karen S. Y.3; Wang, Ya1 ; Geng, Fu-lei 1,3; Li, Zhi 1,3; Cheung, Eric F. C.4
刊名	SCIENTIFIC REPORTS
	2015-07-02
卷号	5 期号:0 页码:11850
ISSN号	2045-2322
英文摘要	The present study examined different types of neurological signs in patients with first-episode schizophrenia and their relationships with neurocognitive functions. Both cross-sectional and longitudinal designs were adopted with the use of the abridged Cambridge Neurological Inventory which comprises items capturing motor coordination, sensory integration and disinhibition. A total of 157 patients with first-episode schizophrenia were assessed at baseline and 101 of them were re-assessed at six-month interval. A structural equation model (SEM) with invariance model across time was used for data analysis. The model fitted well with the data at baseline assessment, X<^>2(21) = 21.78, p = 0.413, NFI = 0.95, NNFI = 1.00, CFI = 1.00, IFI = 1.00, RMSEA = 0.015. Subsequent SEM analysis with invariance model at six-month interval also demonstrated the same stable pattern across time and showed strong measurement invariance and structure invariance across time. Our findings suggest that neurological signs capture more or less the same construct captured by conventional neurocognitive tests in patients with schizophrenia. The measurement and structure of these relationships appear to be stable over time.
收录类别	SCI ; SSCI
语种	英语
WOS记录号	WOS:000357269100001
内容类型	期刊论文
源URL	[http://ir.psych.ac.cn/handle/311026/13341]
专题	心理研究所_中国科学院心理健康重点实验室
作者单位	1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Neuropsychol & Appl Cognit Neurosci Lab, Beijing 100101, Peoples R China 2.Univ Sci & Technol China, Dept Stat & Finance, Hefei 230026, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China 4.Castle Peak Hosp, Hong Kong, Hong Kong, Peoples R China
推荐引用方式 GB/T 7714	Chan, Raymond C. K.,Dai, Shan,Lui, Simon S. Y.,et al. Re-visiting the nature and relationships between neurological signs and neurocognitive functions in first-episode schizophrenia: An invariance model across time[J]. SCIENTIFIC REPORTS,2015,5(0):11850.
APA	Chan, Raymond C. K..,Dai, Shan.,Lui, Simon S. Y..,Ho, Karen K. Y..,Hung, Karen S. Y..,...&Cheung, Eric F. C..(2015).Re-visiting the nature and relationships between neurological signs and neurocognitive functions in first-episode schizophrenia: An invariance model across time.SCIENTIFIC REPORTS,5(0),11850.
MLA	Chan, Raymond C. K.,et al."Re-visiting the nature and relationships between neurological signs and neurocognitive functions in first-episode schizophrenia: An invariance model across time".SCIENTIFIC REPORTS 5.0(2015):11850.