Structural class tendency of polypeptide: A new conception in predicting protein structural class | |
Yu, Tao; Sun, Zhi-Bo; Sang, Han-Ping; Huang, Sheng-You; Zou, Xian-Wu | |
刊名 | PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS |
2007-12-01 | |
卷号 | 386期号:1页码:581-589 |
关键词 | polypeptides structural class tendency protein structural classes |
英文摘要 | Prediction of protein domain structural classes is an important topic in protein science. In this paper, we proposed a new conception: structural class tendency of polypeptides (SCTP), which is based on the fact that a given amino acid fragment tends to be presented in certain type of proteins. The SCTP is obtained from an available training data set PDB40-B. When using the SCTP to predict protein structural classes by Intimate Sorting predictive method, we got the predictive accuracy (jack knife test) with 93.7%, 96.5%, and 78.6% for the testing data set PDB40-j, Chou&Maggiora and CHOU. These results indicate that the SCTP approach is quite encouraging and promising. This new conception provides an effective tool to extract valuable information from protein sequences. (c) 2007 Elsevier B.V. All rights reserved. |
WOS标题词 | Science & Technology ; Physical Sciences |
类目[WOS] | Physics, Multidisciplinary |
研究领域[WOS] | Physics |
关键词[WOS] | AMINO-ACID-COMPOSITION ; GLOBULAR-PROTEINS ; NEURAL-NETWORKS ; FOLDING TYPES ; DOMAIN ; CLASSIFICATION ; SEQUENCE ; RECOGNITION ; CHARACTERS ; SECONDARY |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000251438800052 |
公开日期 | 2015-09-08 |
内容类型 | 期刊论文 |
源URL | [http://ir.wipm.ac.cn/handle/112942/7806] |
专题 | 武汉物理与数学研究所_2011年以前论文发表(包括2011年) |
作者单位 | 1.Wuhan Univ, Dept Phys, Wuhan 430072, Peoples R China 2.Wuhan Inst Phys & Math, CAS, Wuhan 430071, Peoples R China 3.Jianghan Univ, Dept Phys, Wuhan 430071, Peoples R China |
推荐引用方式 GB/T 7714 | Yu, Tao,Sun, Zhi-Bo,Sang, Han-Ping,et al. Structural class tendency of polypeptide: A new conception in predicting protein structural class[J]. PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS,2007,386(1):581-589. |
APA | Yu, Tao,Sun, Zhi-Bo,Sang, Han-Ping,Huang, Sheng-You,&Zou, Xian-Wu.(2007).Structural class tendency of polypeptide: A new conception in predicting protein structural class.PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS,386(1),581-589. |
MLA | Yu, Tao,et al."Structural class tendency of polypeptide: A new conception in predicting protein structural class".PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS 386.1(2007):581-589. |
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