Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology

CORC > 自动化研究所 > 中国科学院自动化研究所 > 中国科学院分子影像重点实验室

	Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology
	Chi, Chongwei1 ; Du, Yang1 ; Ye, Jinzuo1 ; Kou, Deqiang 3; Qiu, Jingdan 3; Wang, Jiandong 3; Tian, Jie1 ; Chen, Xiaoyuan 2
刊名	THERANOSTICS
	2014
卷号	4 期号:11 页码:1072-1084
关键词	Optical molecular imaging Intraoperative imaging-guided cancer surgery Near-infrared fluorescence Multi-modality Imaging Indocyanine green
英文摘要	Cancer is a major threat to human health. Diagnosis and treatment using precision medicine is expected to be an effective method for preventing the initiation and progression of cancer. Although anatomical and functional imaging techniques such as radiography, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) have played an important role for accurate preoperative diagnostics, for the most part these techniques cannot be applied intraoperatively. Optical molecular imaging is a promising technique that provides a high degree of sensitivity and specificity in tumor margin detection. Furthermore, existing clinical applications have proven that optical molecular imaging is a powerful intraoperative tool for guiding surgeons performing precision procedures, thus enabling radical resection and improved survival rates. However, detection depth limitation exists in optical molecular imaging methods and further breakthroughs from optical to multi-modality intraoperative imaging methods are needed to develop more extensive and comprehensive intraoperative applications. Here, we review the current intraoperative optical molecular imaging technologies, focusing on contrast agents and surgical navigation systems, and then discuss the future prospects of multi-modality imaging technology for intraoperative imaging-guided cancer surgery.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Medicine, Research & Experimental
研究领域[WOS]	Research & Experimental Medicine
关键词[WOS]	SENTINEL LYMPH-NODE ; NEAR-INFRARED FLUORESCENCE ; INDOCYANINE GREEN FLUORESCENCE ; EARLY GASTRIC-CANCER ; CELL-PENETRATING PEPTIDES ; HUMAN SERUM-ALBUMIN ; IMMOBILIZED DIAGNOSTIC KIT ; FLAP BREAST RECONSTRUCTION ; CYSTEINE PROTEASE ACTIVITY ; ACTIVITY-BASED PROBES
收录类别	SCI
语种	英语
WOS记录号	WOS:000345212900002
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/4112]
专题	自动化研究所_中国科学院分子影像重点实验室
作者单位	1.Chinese Acad Sci, Inst Automat, Key Lab Mol Imaging Chinese Acad Sci, Beijing 100190, Peoples R China 2.NIBIB, NIH, Lab Mol Imaging & Nanomed, Bethesda, MD 20814 USA 3.Gen Hosp Peoples Liberat Army, Dept Gen Surg, Beijing 100853, Peoples R China
推荐引用方式 GB/T 7714	Chi, Chongwei,Du, Yang,Ye, Jinzuo,et al. Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology[J]. THERANOSTICS,2014,4(11):1072-1084.
APA	Chi, Chongwei.,Du, Yang.,Ye, Jinzuo.,Kou, Deqiang.,Qiu, Jingdan.,...&Chen, Xiaoyuan.(2014).Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology.THERANOSTICS,4(11),1072-1084.
MLA	Chi, Chongwei,et al."Intraoperative Imaging-Guided Cancer Surgery: From Current Fluorescence Molecular Imaging Methods to Future Multi-Modality Imaging Technology".THERANOSTICS 4.11(2014):1072-1084.