Helical optical projection tomography

CORC > 自动化研究所 > 中国科学院自动化研究所 > 中国科学院分子影像重点实验室

	Helical optical projection tomography
	Arranz, Alicia 1; Dong, Di2 ; Zhu, Shouping 3; Rudin, Markus 1; Tsatsanis, Christos 4; Tian, Jie2,3 ; Ripoll, Jorge 5,6,7
刊名	OPTICS EXPRESS
	2013-11-04
卷号	21 期号:22 页码:25912-25925
英文摘要	A new technique termed Helical Optical Projection Tomography (hOPT) has been developed with the aim to overcome some of the limitations of current 3D optical imaging techniques. hOPT is based on Optical Projection Tomography (OPT) with the major difference that there is a translation of the sample in the vertical direction during the image acquisition process, requiring a new approach to image reconstruction. Contrary to OPT, hOPT makes possible to obtain 3D-optical images of intact long samples without imposing limits on the sample length. This has been tested using hOPT to image long murine tissue samples such as spinal cords and large intestines. Moreover, 3D-reconstructed images of the colon of DSS-treated mice, a model for Inflammatory Bowel Disease, allowed the identification of the structural alterations. Finally, the geometry of the hOPT device facilitates the addition of a Selective Plane Illumination Microscopy (SPIM) arm, providing the possibility of delivering high resolution images of selected areas together with complete volumetric information. (C) 2013 Optical Society of America
WOS标题词	Science & Technology ; Physical Sciences
类目[WOS]	Optics
研究领域[WOS]	Optics
关键词[WOS]	PLANE ILLUMINATION MICROSCOPY ; LIGHT-SHEET MICROSCOPY ; GENE-EXPRESSION ; RESOLUTION ; VISUALIZATION ; SPECIMENS ; BRAIN ; DEEP
收录类别	SCI
语种	英语
WOS记录号	WOS:000327007800053
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/4104]
专题	自动化研究所_中国科学院分子影像重点实验室
作者单位	1.Swiss Fed Inst Technol, Inst Biomed Engn, CH-8093 Zurich, Switzerland 2.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China 3.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China 4.Univ Crete, Sch Med, Lab Clin Chem, Iraklion 71003, Greece 5.Fdn Res & Technol Hellas FORTH, Inst Elect Struct & Laser, Iraklion 71110, Greece 6.Univ Carlos III Madrid, Dept Bioengn & Aerosp Engn, Madrid 28911, Spain 7.Hosp Gen Gregorio Maranon, Inst Invest Sanitaria, Expt Med & Surg Unit, Madrid 28007, Spain
推荐引用方式 GB/T 7714	Arranz, Alicia,Dong, Di,Zhu, Shouping,et al. Helical optical projection tomography[J]. OPTICS EXPRESS,2013,21(22):25912-25925.
APA	Arranz, Alicia.,Dong, Di.,Zhu, Shouping.,Rudin, Markus.,Tsatsanis, Christos.,...&Ripoll, Jorge.(2013).Helical optical projection tomography.OPTICS EXPRESS,21(22),25912-25925.
MLA	Arranz, Alicia,et al."Helical optical projection tomography".OPTICS EXPRESS 21.22(2013):25912-25925.