Reconstruction of fluorescence molecular tomography via a nonmonotone spectral projected gradient pursuit method

CORC > 自动化研究所 > 中国科学院自动化研究所 > 中国科学院分子影像重点实验室

	Reconstruction of fluorescence molecular tomography via a nonmonotone spectral projected gradient pursuit method
	Ye, Jinzuo1 ; Du, Yang1 ; An, Yu 2; Chi, Chongwei1 ; Tian, Jie1
刊名	JOURNAL OF BIOMEDICAL OPTICS
	2014-12-01
卷号	19 期号:12 页码:-
关键词	fluorescence molecular tomography image reconstruction inverse problems nonmonotone spectral projected gradient pursuit tumor detection in vivo imaging
英文摘要	Fluorescence molecular tomography (FMT) is a promising imaging technique in preclinical research, enabling three-dimensional location of the specific tumor position for small animal imaging. However, FMT presents a challenging inverse problem that is quite ill-posed and ill-conditioned. Thus, the reconstruction of FMT faces various challenges in its robustness and efficiency. We present an FMT reconstruction method based on nonmonotone spectral projected gradient pursuit (NSPGP) with l(1)-norm optimization. At each iteration, a spectral gradient-projection method approximately minimizes a least-squares problem with an explicit onenorm constraint. A nonmonotone line search strategy is utilized to get the appropriate updating direction, which guarantees global convergence. Additionally, the Barzilai-Borwein step length is applied to build the optimal step length, further improving the convergence speed of the proposed method. Several numerical simulation studies, including multisource cases as well as comparative analyses, have been performed to evaluate the performance of the proposed method. The results indicate that the proposed NSPGP method is able to ensure the accuracy, robustness, and efficiency of FMT reconstruction. Furthermore, an in vivo experiment based on a heterogeneous mouse model was conducted, and the results demonstrated that the proposed method held the potential for practical applications of FMT. (C) 2014 Society of Photo-Optical Instrumentation Engineers (SPIE)
WOS标题词	Science & Technology ; Life Sciences & Biomedicine ; Physical Sciences
类目[WOS]	Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
研究领域[WOS]	Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging
关键词[WOS]	DIFFUSE OPTICAL TOMOGRAPHY ; ELEMENT BASED TOMOGRAPHY ; IMAGE-RECONSTRUCTION ; SPARSITY REGULARIZATION ; LINE SEARCH ; ALGORITHM ; LIGHT ; INFORMATION ; BARZILAI ; SYSTEM
收录类别	SCI
语种	英语
WOS记录号	WOS:000347442600018
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/4072]
专题	自动化研究所_中国科学院分子影像重点实验室
作者单位	1.Chinese Acad Sci, Key Lab Mol Imaging, Inst Automat, Beijing 100190, Peoples R China 2.Beijing Jiaotong Univ, Sch Comp & Informat Technol, Dept Biomed Engn, Beijing 100044, Peoples R China
推荐引用方式 GB/T 7714	Ye, Jinzuo,Du, Yang,An, Yu,et al. Reconstruction of fluorescence molecular tomography via a nonmonotone spectral projected gradient pursuit method[J]. JOURNAL OF BIOMEDICAL OPTICS,2014,19(12):-.
APA	Ye, Jinzuo,Du, Yang,An, Yu,Chi, Chongwei,&Tian, Jie.(2014).Reconstruction of fluorescence molecular tomography via a nonmonotone spectral projected gradient pursuit method.JOURNAL OF BIOMEDICAL OPTICS,19(12),-.
MLA	Ye, Jinzuo,et al."Reconstruction of fluorescence molecular tomography via a nonmonotone spectral projected gradient pursuit method".JOURNAL OF BIOMEDICAL OPTICS 19.12(2014):-.