Recent Advances in Cerenkov Luminescence and Tomography Imaging
Qin, Chenghu1; Zhong, Jianghong1; Hu, Zhenhua2; Yang, Xin1; Tian, Jie1
刊名IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
2012-05-01
卷号18期号:3页码:1084-1093
关键词Cerenkov luminescence imaging (CLI) Cerenkov luminescence tomography (CLT) molecular imaging multimodality imaging nuclear imaging optical imaging optical tomography radionuclides
英文摘要Molecular imaging can provide qualitative or quantitative physiological and pathological knowledge at the cellular and molecular levels for biomedical research, which has experienced a remarkable growth in recent years. Among molecular imaging techniques, optical molecular imaging has attracted considerable attention in view of its excellent performance and high cost-effectiveness. However, heretofore the experimental objects of optical imaging technique are mainly small animals like rats and mice, and optical imaging can hardly be used for clinical research not only because of the limited tissue penetration, but also due to the scarcity of appropriate imaging probes. As a newly emerging and very promising imaging modality, Cerenkov luminescence employs light signals emitting from radionuclides used in nuclear imaging based on Cerenkov radiation, which can provide more potential optical imaging probes for clinical application and facilitate the realization of multimodality imaging. In this paper, the fundamentals of Cerenkov luminescence are first introduced, and then Cerenkov luminescence imaging and tomography as well as the corresponding biomedical applications are represented. Finally, limitations of Cerenkov luminescence and the discussion of this contribution are covered.
WOS标题词Science & Technology ; Technology ; Physical Sciences
类目[WOS]Engineering, Electrical & Electronic ; Optics ; Physics, Applied
研究领域[WOS]Engineering ; Optics ; Physics
关键词[WOS]SPHERICAL-HARMONICS APPROXIMATION ; POSITRON-EMITTING RADIOTRACERS ; RADIATIVE-TRANSFER EQUATION ; BIOLUMINESCENCE TOMOGRAPHY ; FINITE-TEMPERATURE ; LIGHT-PROPAGATION ; PHOTON MIGRATION ; HETEROGENEOUS TISSUES ; CHERENKOV RADIATION ; LIVING SUBJECTS
收录类别SCI
语种英语
WOS记录号WOS:000306524300006
内容类型期刊论文
源URL[http://ir.ia.ac.cn/handle/173211/4059]  
专题自动化研究所_中国科学院分子影像重点实验室
作者单位1.Chinese Acad Sci, Inst Automat, Intelligent Med Res Ctr, Beijing 100190, Peoples R China
2.Xidian Univ, Life Sci Res Ctr, Sch Life Sci & Technol, Xian 710071, Peoples R China
推荐引用方式
GB/T 7714
Qin, Chenghu,Zhong, Jianghong,Hu, Zhenhua,et al. Recent Advances in Cerenkov Luminescence and Tomography Imaging[J]. IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS,2012,18(3):1084-1093.
APA Qin, Chenghu,Zhong, Jianghong,Hu, Zhenhua,Yang, Xin,&Tian, Jie.(2012).Recent Advances in Cerenkov Luminescence and Tomography Imaging.IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS,18(3),1084-1093.
MLA Qin, Chenghu,et al."Recent Advances in Cerenkov Luminescence and Tomography Imaging".IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS 18.3(2012):1084-1093.
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