Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study

CORC > 自动化研究所 > 中国科学院自动化研究所 > 中国科学院分子影像重点实验室

	Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study
	Sun, Jinbo 1; Zhu, Yuanqiang 1; Jin, Lingmin 1; Yang, Yang 1; von Deneen, KarenM.1; Qin, Wei 1; Gong, Qiyong 2; Tian, Jie1,3
刊名	EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
	2012
页码	-
英文摘要	Nowadays, functional magnetic resonance imaging (fMRI) has become one of the most important ways to explore the central mechanism of acupuncture. Among these studies, activations around the somatosensory-related brain network had the most robust blood oxygen level-dependent (BOLD) responses. However, due to the insufficient control of the subjective sensations during acupuncture stimulation, whether these robust activations reflected the pattern of de-qi, sharp pain, or mixed (de-qi + sharp pain) sensations was largely unknown. The current study recruited 50 subjects and grouped them into two groups according to whether he/she experienced sharp pain during acupuncture stimulation to give a definite answer to the aforesaid question. Our results indicated that BOLD responses associated with de-qi during acupuncture stimulation at ST36 were activation dominated. Furthermore, both the quantitative and qualitative differences of BOLD responses between de-qi and mixed sensations evoked by acupuncture stimulation were significant. The pattern of BOLD responses of sharp pain might be partly separated from that of de-qi in the spatial distribution. Therefore, we proposed that in order to explore the specific central mechanism of acupuncture, subjects with sharp pain should be excluded from those with only de-qi.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Integrative & Complementary Medicine
研究领域[WOS]	Integrative & Complementary Medicine
关键词[WOS]	EVOKED-POTENTIALS ; FUNCTIONAL MRI ; GLOBAL SIGNAL ; ELECTROACUPUNCTURE STIMULATION ; ELECTRICAL-STIMULATION ; CORTICAL NETWORK ; BRAIN ACTIVITY ; LIMBIC SYSTEM ; MUSCLE PAIN ; SKIN
收录类别	SCI
语种	英语
WOS记录号	WOS:000313191200001
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/4054]
专题	自动化研究所_中国科学院分子影像重点实验室
作者单位	1.Xidian Univ, Sch Life Sci & Technol, Life Sci Res Ctr, Xian 710071, Shaanxi, Peoples R China 2.Sichuan Univ, W China Hosp, Dept Radiol, Huaxi MR Res Ctr HMRRC,Ctr Med Imaging, Chengdu 610041, Sichuan, Peoples R China 3.Chinese Acad Sci, Inst Automat, Beijing 100190, Peoples R China
推荐引用方式 GB/T 7714	Sun, Jinbo,Zhu, Yuanqiang,Jin, Lingmin,et al. Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study[J]. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,2012:-.
APA	Sun, Jinbo.,Zhu, Yuanqiang.,Jin, Lingmin.,Yang, Yang.,von Deneen, KarenM..,...&Tian, Jie.(2012).Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study.EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE,-.
MLA	Sun, Jinbo,et al."Partly Separated Activations in the Spatial Distribution between de-qi and Sharp Pain during Acupuncture Stimulation: An fMRI-Based Study".EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2012):-.