Volumetric variation in subregions of the cerebellum correlates with working memory performance

	Volumetric variation in subregions of the cerebellum correlates with working memory performance
	Ding, Hui 1; Qin, Wen 1; Jiang, Tianzi2 ; Zhang, Yunting 1; Yu, Chunshui 1
刊名	NEUROSCIENCE LETTERS
	2012-02-02
卷号	508 期号:1 页码:47-51
关键词	Working memory Voxel-based morphometry Cerebellum Magnetic resonance imaging
英文摘要	We aimed to investigate the relationship between structural variations in the cerebellum and individual differences in working memory performance as assessed by average reaction time (RT) and correction rate (CR) on a 3-back task. High-resolution T1-weighted magnetic resonance images were acquired in 311 healthy young adults. Voxel-based morphometry (VBM) was used to identify cerebellar areas with volumes correlated to working memory performance when controlling for age, gender, years of education and handedness. We found that RT was positively correlated with the grey matter volume (GMV) bilaterally in cerebellar lobules IV/V, VI and VIII, in vermis VII/VIII and in left Crus I; CR was positively correlated with the GMV in the left lobule VI and Crus I. These findings suggest that RT on a working memory task is related to structural variation in both motor and cognitive subregions of the cerebellum, while CR is mainly associated with the cognitive subregions. Our findings provide further evidence that the cerebellum contributes to working memory function. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
WOS标题词	Science & Technology ; Life Sciences & Biomedicine
类目[WOS]	Neurosciences
研究领域[WOS]	Neurosciences & Neurology
关键词[WOS]	COGNITIVE-AFFECTIVE SYNDROME ; CORTICAL THICKNESS ; FUNCTIONAL TOPOGRAPHY ; ALZHEIMERS-DISEASE ; MOTOR ; FMRI ; COORDINATION ; NETWORKS ; CORTEX ; METAANALYSIS
收录类别	SCI
语种	英语
WOS记录号	WOS:000301831100011
内容类型	期刊论文
源URL	[http://ir.ia.ac.cn/handle/173211/3220]
专题	自动化研究所_脑网络组研究中心
作者单位	1.Tianjin Med Univ, Dept Radiol, Gen Hosp, Tianjin 300052, Peoples R China 2.Chinese Acad Sci, LIAMA Ctr Computat Med, Natl Lab Pattern Recognit, Inst Automat, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Ding, Hui,Qin, Wen,Jiang, Tianzi,et al. Volumetric variation in subregions of the cerebellum correlates with working memory performance[J]. NEUROSCIENCE LETTERS,2012,508(1):47-51.
APA	Ding, Hui,Qin, Wen,Jiang, Tianzi,Zhang, Yunting,&Yu, Chunshui.(2012).Volumetric variation in subregions of the cerebellum correlates with working memory performance.NEUROSCIENCE LETTERS,508(1),47-51.
MLA	Ding, Hui,et al."Volumetric variation in subregions of the cerebellum correlates with working memory performance".NEUROSCIENCE LETTERS 508.1(2012):47-51.