Life without A tail: New formats of long noncoding RNAs
Zhang, Y; Yang, L; Chen, LL
刊名INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
2014
卷号54期号:1页码:338-349
关键词nonpolyadenylated RNAs MALAT1 NEAT1 sno-IncRNAs circular RNAs ciRNAs
通讯作者Chen, LL (reprint author), Inst Biochem & Cell Biol, State Key Lab Mol Biol, Shanghai, Peoples R China.,linglingchen@sibcb.ac.cn
英文摘要While most long noncoding RNAs (lncRNAs) appear indistinguishable from mRNAs, having 5' cap structures and 3' poly(A) tails, recent work has revealed new formats. Rather than taking advantage of the canonical cleavage and polyadenylation for their 3' end maturation, such lncRNAs are processed and stablized by a number of other mechanisms, including the RNase P cleavage to generate a mature 3' end, or capped by snoRNP complexes at both ends, or by forming circular structures. Importantly, such lncRNAs have also been implicated in gene expression regulation in mammalian cells. Here, we highlight recent progress in our understanding of the biogenesis and function of lncRNAs without a poly(A) tail. (C) 2013 Elsevier Ltd. All rights reserved.
学科主题Biochemistry & Molecular Biology; Cell Biology
类目[WOS]Biochemistry & Molecular Biology ; Cell Biology
关键词[WOS]SMALL NUCLEOLAR RNA ; PRADER-WILLI-SYNDROME ; NUCLEAR-BODIES ; GENE-EXPRESSION ; MESSENGER-RNAS ; CIRCULAR RNAS ; TRIPLE-HELIX ; SACCHAROMYCES-CEREVISIAE ; ALTERNATIVE CLEAVAGE ; MICRORNA SPONGES
收录类别SCI
语种英语
WOS记录号WOS:000342524600036
内容类型期刊论文
版本出版稿
源URL[http://202.127.25.143/handle/331003/295]  
专题上海生化细胞研究所_上海生科院生化细胞研究所
推荐引用方式
GB/T 7714
Zhang, Y,Yang, L,Chen, LL. Life without A tail: New formats of long noncoding RNAs[J]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY,2014,54(1):338-349.
APA Zhang, Y,Yang, L,&Chen, LL.(2014).Life without A tail: New formats of long noncoding RNAs.INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY,54(1),338-349.
MLA Zhang, Y,et al."Life without A tail: New formats of long noncoding RNAs".INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY 54.1(2014):338-349.
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