Identification of differentially expressed miRNAs in mouse spinal cord development

	Identification of differentially expressed miRNAs in mouse spinal cord development
	Zhao, BT; Huang, MG; Bai, YY; Fan, CS; Fan, Y; Jin, YX
刊名	ACTA BIOCHIMICA ET BIOPHYSICA SINICA
	2015
卷号	47 期号:3 页码:224-229
关键词	miRNA spinal cord development miRNA microarray
通讯作者	Jin, YX (reprint author), Shanghai Univ, Sch Life Sci, Shanghai 200444, Peoples R China.,yi.fan@uphs.upenn.edu ; yxjin@sibs.ac.cn
英文摘要	MicroRNAs (miRNAs) are a class of non-coding, regulatory small RNAs of similar to 22 nt. It was implicated that these small RNAs play critical roles in various important biological processes. During development, some miRNAs are specifically expressed in individual tissues and at particular developmental stages. Many miRNAs show distinct expression patterns in the development of central nervous system, including spinal cord. In this study, we first reported the miRNAs expression in the development of mouse spinal cord. Differentially expressed miRNAs in embryonic (day 13.5) and neonatal mice spinal cords were identified. The predicted target genes of the differentially expressed miRNAs were subject to gene ontology and KEGG pathway analysis, and several nervous development-related pathways were enriched, implying that these miRNAs may be involved in these pathways that regulate mouse spinal cord development.
学科主题	Biochemistry & Molecular Biology; Biophysics
类目[WOS]	Biochemistry & Molecular Biology ; Biophysics
关键词[WOS]	CENTRAL-NERVOUS-SYSTEM ; MICRORNA TARGETS ; INJURY ; DYSREGULATION ; PREDICTION ; RESOURCE ; DISEASE ; CLUSTER ; UPDATE ; SITES
收录类别	SCI
语种	英语
WOS记录号	WOS:000351136700010
内容类型	期刊论文
版本	出版稿
源URL	[http://202.127.25.143/handle/331003/36]
专题	上海生化细胞研究所_上海生科院生化细胞研究所
推荐引用方式 GB/T 7714	Zhao, BT,Huang, MG,Bai, YY,et al. Identification of differentially expressed miRNAs in mouse spinal cord development[J]. ACTA BIOCHIMICA ET BIOPHYSICA SINICA,2015,47(3):224-229.
APA	Zhao, BT,Huang, MG,Bai, YY,Fan, CS,Fan, Y,&Jin, YX.(2015).Identification of differentially expressed miRNAs in mouse spinal cord development.ACTA BIOCHIMICA ET BIOPHYSICA SINICA,47(3),224-229.
MLA	Zhao, BT,et al."Identification of differentially expressed miRNAs in mouse spinal cord development".ACTA BIOCHIMICA ET BIOPHYSICA SINICA 47.3(2015):224-229.