Steroidal saponins with cytotoxic activity from the rhizomes of Paris polyphylla var. yunnanensis

CORC > 昆明植物研究所 > 中国科学院昆明植物研究所 > 植物化学与西部植物资源持续利用国家重点实验室

	Steroidal saponins with cytotoxic activity from the rhizomes of Paris polyphylla var. yunnanensis
	Wen, Yan-Shi 1,2; Ni, Wei 1; Qin, Xu-Jie1 ; Yan, Huan 1; Chen, Chang-Xiang1 ; Hua, Yan 2; Cheng, Yung-Chi 3; He, Li 4; Liu, Hai-Yang1
刊名	PHYTOCHEMISTRY LETTERS
	2015-06-01
卷号	12 页码:31-34
关键词	Paris polyphylla var. yunnanensis Steroidal saponins Dianchonglouoside A Dianchonglouoside B Cytotoxic activity
通讯作者	Liu,HY (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China. ; haiyangliu@mail.kib.ac.cn
英文摘要	Two previously unreported spirostanol saponins, dianchonglouosides A and B (1 and 2), along with 7 known steroidal saponins (3-9) were isolated from the rhizomes of Paris polyphylla var. yunnanensis. Their structures were elucidated by extensive spectroscopic analysis (MS, 1D, and 2D NMR), and chemical methods. The cytotoxic activities of the isolated compounds 1-9 were also evaluated against two human cancer cell lines (HEK293 and HepG2). The results showed that compound 7 had the strongest cytotoxic activity against the two cancer cell lines with the IC50 values of 0.6 and 0.9 mM, respectively. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
学科主题	Biochemistry & Molecular Biology; Plant Sciences
类目[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
研究领域[WOS]	Biochemistry & Molecular Biology ; Plant Sciences
关键词[WOS]	PALMAE PLANTS ; CONSTITUENTS ; GLYCOSIDES ; LEAVES
收录类别	SCI
语种	英语
WOS记录号	WOS:000356336400007
内容类型	期刊论文
源URL	[http://ir.kib.ac.cn/handle/151853/21335]
专题	昆明植物研究所_植物化学与西部植物资源持续利用国家重点实验室
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 2.Southwest Forestry Univ, Coll Forestry, Kunming 650224, Peoples R China 3.Yale Univ, Sch Med, Dept Pharmacol, New Haven, CT 06510 USA 4.Kunming Med Univ, Affiliated Hosp 1, Dept Dermatol, Kunming 650032, Peoples R China
推荐引用方式 GB/T 7714	Wen, Yan-Shi,Ni, Wei,Qin, Xu-Jie,et al. Steroidal saponins with cytotoxic activity from the rhizomes of Paris polyphylla var. yunnanensis[J]. PHYTOCHEMISTRY LETTERS,2015,12:31-34.
APA	Wen, Yan-Shi.,Ni, Wei.,Qin, Xu-Jie.,Yan, Huan.,Chen, Chang-Xiang.,...&Liu, Hai-Yang.(2015).Steroidal saponins with cytotoxic activity from the rhizomes of Paris polyphylla var. yunnanensis.PHYTOCHEMISTRY LETTERS,12,31-34.
MLA	Wen, Yan-Shi,et al."Steroidal saponins with cytotoxic activity from the rhizomes of Paris polyphylla var. yunnanensis".PHYTOCHEMISTRY LETTERS 12(2015):31-34.